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BioWorld - Saturday, January 17, 2026
Home » Keywords » Silexion Therapeutics Corp.

Items Tagged with 'Silexion Therapeutics Corp.'

ARTICLES

Cancer cell, dropper, test tubes
Cancer

Silexion’s SIL-204 shows promise in pancreatic, colorectal and lung cancer cell lines

May 30, 2025
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Silexion Therapeutics Corp. has released preclinical data demonstrating the efficacy of its next-generation RNA interference (RNAi) therapeutic candidate, SIL-204, against human pancreatic, colorectal and lung cancer cell lines.


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3D illustration of pancreatic cancer
Cancer

Silexion plans dual-route strategy for SIL-204 for KRAS-driven pancreatic cancer

March 31, 2025
Silexion Therapeutics Corp. has announced an expanded development plan for its next-generation siRNA candidate SIL-204. The new dual-route strategy will integrate intratumoral and systemic administration to target both primary tumors and metastases, respectively, to treat KRAS-driven pancreatic cancer.
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Illustration of cancer in the pancreas
Cancer

Silexion completes study of SIL-204 in orthotopic pancreatic cancer models

Feb. 26, 2025
Silexion Therapeutics Corp. has completed its initial study evaluating SIL-204 in orthotopic pancreatic cancer models. SIL-204 is a next-generation siRNA candidate designed to target a broad range of KRAS mutations.
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Cancer cells
Cancer

Next-generation siRNA successfully silences multiple KRAS mutations

Feb. 4, 2025
KRAS G12D and G12V mutations are highly prevalent in aggressive gastrointestinal tumor types such as pancreatic cancer.
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Cancer

SIL-204 shows synergistic activity with 5-FU and irinotecan in pancreatic cancer studies

Jan. 16, 2025
Silexion Therapeutics Corp. has released new preclinical results demonstrating the synergistic efficacy of its proprietary second-generation siRNA candidate, SIL-204, in combination with components of first-line chemotherapy for pancreatic cancer.
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