• Sign In
  • Sign Out
  • My Account
Subscribe
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
  • Special reports
Clarivate
  • Data Snapshots
  • BioWorld
  • BioWorld MedTech
  • Infographics: Dynamic digital data analysis
  • Special reports
  • Infographics: Dynamic digital data analysis
  • Trump administration impacts
  • Biopharma M&A scorecard
  • BioWorld 2024 review
  • BioWorld MedTech 2024 review
  • BioWorld Science 2024 review
  • Women's health
  • China's GLP-1 landscape
  • PFA re-energizes afib market
  • China CAR T
  • Alzheimer's disease
  • Israel
  • Rise of obesity
  • Radiopharmaceuticals
  • Biosimilars
  • Aging
  • IVDs on the rise
  • Coronavirus
  • Artificial intelligence

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Israel
    • Rise of obesity
    • Radiopharmaceuticals
    • Biosimilars
    • Aging
    • IVDs on the rise
    • Coronavirus
    • Artificial intelligence

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe
Home » Newsletters » BioWorld

BioWorld

Dec. 19, 2017

View Archived Issues

Autifony’s ion channel approach draws potential $741M Boehringer Ingelheim deal

LONDON – Boehringer Ingelheim GmbH has agreed to pay up €627.5 million (US$741.3 million) to buy Autifony Therapeutics Ltd.’s lead program, AUT-00206 and the associated ion channel modulation technology through which the compound was discovered. Read More

Regulatory front

The Center for Drug Evaluation and Research at the FDA has issued a draft guidance for information requests and discipline review letters under the generic drug user fee agreement, stating that reviewers will ordinarily communicate their views of possible deficiencies in a generic drug application via a discipline review letter (DRL) as each discipline involved in the review completes its portion of the application. Read More

Other news to note

Aerie Pharmaceuticals Inc., of Irvine, Calif., said the FDA approved Rhopressa (netarsudil ophthalmic solution) 0.02 percent for the lowering of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Read More

ISA, Regeneron to test vaccine-PD-1 combo in HPV16-associated cancers

DUBLIN – ISA Pharmaceuticals BV could earn well in excess of $500 million from a strategic collaboration in immuno-oncology with Regeneron Pharmaceuticals Inc., which marries its peptide-based therapeutic cancer vaccine, ISA-101, with Regeneron’s PD-1 inhibitor, cemiplimab (REGN-2810). Read More

Aptinyx refuels with $70M series B for NMDA modulators

Aptinyx Inc. continued to race down the track by completing a $70 million series B financing to continue advancing its pipeline of N-methyl-D-aspartate (NMDA) receptor modulators. Read More

Mesoblast IP agreement shores up Tigenix’s rights in adult stem cell market

PERTH, Australia – Belgium’s Tigenix NV licensed intellectual property from Australian stem cell company Mesoblast Ltd. the same day it announced approval of the EU’s first allogeneic stem cell therapy. Read More

FDA draft seeks to clarify policy on drug study IVDs

With the age of the companion diagnostic fast approaching, the FDA recently issued a draft guidance dealing with the use of investigational in vitro diagnostics (IVD) in drug studies, highlighting the circumstances in which the use of that IVD rises from an insignificant to a significant risk, thus incurring a regulatory liability. Read More

Australian R&D investment down, but VC activity on the rise, says innovation report

PERTH, Australia – Investment in research and development fell sharply in the last decade in Australia, and the government can play an important role to improve framework conditions that support innovation, according to the Australian Innovation System Report 2017. Read More

Financings

Madrigal Pharmaceuticals Inc., of Conshohocken, Pa., said it launched a public offering of $100 million of its common stock, and intends to grant underwriters a 30-day option to purchase up to an additional 15 percent. Read More

In the clinic

La Jolla Pharmaceutical Co., of San Diego, started the phase II LJ401-HH01 trial testing LJPC-401 (synthetic human hepcidin) in approximately 60 patients with hereditary hemochromatosis. The trial will measure the change in transferrin saturation from baseline to the end of the 12-week treatment compared to placebo as the primary endpoint. Change in serum ferritin from baseline to end of treatment and the requirement for and frequency of phlebotomy procedures – removal of blood – during the study will be measured as secondary endpoints. Read More

Popular Stories

  • Today's news in brief

    BioWorld
    BioWorld briefs for June 6, 2025.
  • Today's news in brief

    BioWorld MedTech
    BioWorld MedTech briefs for June 6, 2025.
  • News in brief

    BioWorld Asia
    BioWorld Asia briefs for June 3, 2025
  • Biotech deal illustration

    City hits the town with $1B-plus deal with Biogen

    BioWorld
    A development deal with Biogen Inc. could eventually bring City Therapeutics Inc. about $1 billion in milestone payments. It’s a step in the direction the company...
  • Cancer cell in the cross-hairs

    Pan-cancer proteome atlas reveals new biomarkers and targets

    BioWorld Science
    An international group of scientists has completed the first draft of The Pan-Cancer Proteome Atlas (TPCPA). The project is based on mass spectrometry of 22...
  • BioWorld
    • Today's news
    • Analysis and data insight
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld MedTech
    • Today's news
    • Clinical
    • Data Snapshots
    • Deals and M&A
    • Financings
    • Newco news
    • Opinion
    • Regulatory
    • Science
  • BioWorld Asia
    • Today's news
    • Analysis and data insight
    • Australia
    • China
    • Clinical
    • Deals and M&A
    • Financings
    • Newco news
    • Regulatory
    • Science
  • BioWorld Science
    • Today's news
    • Biomarkers
    • Cancer
    • Conferences
    • Endocrine/Metabolic
    • Immune
    • Infection
    • Neurology/Psychiatric
    • Patents
  • More
    • About
    • Advertise with BioWorld
    • Archives
    • Article reprints and permissions
    • Contact us
    • Cookie policy
    • Copyright notice
    • Data methodology
    • Infographics: Dynamic digital data analysis
    • Podcasts
    • Privacy policy
    • Share your news with BioWorld
    • Staff
    • Terms of use
    • Topic alerts
Follow Us

Copyright ©2025. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing

BioWorld. Link to homepage.

Clarivate
  • BioWorld
  • BioWorld MedTech
  • BioWorld Asia
  • BioWorld Science
  • Data Snapshots
    • BioWorld
    • BioWorld MedTech
    • Infographics: Dynamic digital data analysis
  • Special reports
    • Infographics: Dynamic digital data analysis
    • Trump administration impacts
    • Biopharma M&A scorecard
    • BioWorld 2024 review
    • BioWorld MedTech 2024 review
    • BioWorld Science 2024 review
    • Women's health
    • China's GLP-1 landscape
    • PFA re-energizes afib market
    • China CAR T
    • Alzheimer's disease
    • Israel
    • Rise of obesity
    • Radiopharmaceuticals
    • Biosimilars
    • Aging
    • IVDs on the rise
    • Coronavirus
    • Artificial intelligence

BioWorld. Link to homepage.

  • Sign In
  • Sign Out
  • My Account
Subscribe