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Home » Newsletters » BioWorld

BioWorld

Feb. 25, 2019

View Archived Issues

Bench Press: BioWorld looks at translational medicine

Scientists at the Technical University of Munich have demonstrated that sodium chloride increased the responses of T helper 2 (TH2) cells through several different mechanisms. Read More

Regulatory actions for Feb. 22, 2019

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Clinical data for Feb. 22, 2019

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Financings

Nanosphere Health Sciences Inc., of Denver, said it closed its nonbrokered private placement and issued 6.66 million units at 30 cents per unit for gross proceeds of $1.99 million. Read More

Other news to note

Brainstorm Cell Therapeutics Inc., of New York, said the Cleveland Clinic will be the first U.S. clinical site contracted for a planned phase II open-label, multicenter study of repeated intrathecal administration of autologous MSC-NTF cells in participants with progressive multiple sclerosis. Read More

Cancer-focused biopharma companies could be M&A targets

Investors have warmed to the biopharmaceutical sector since the beginning of the year, and they are anticipating that there will be an increase in the number of M&A transactions going forward. They are looking particularly at companies in the oncology space following Eli Lilly and Co.'s $8 billion buyout of Loxo Oncology Inc. last month. Read More

Chinese drugmakers ride wave of VAT cuts on rare diseases

HONG KONG – Chinese drugmakers have gotten a boost in the wake of the Chinese government's announcement to cut the value-added tax (VAT) on treatments for a range of rare diseases, in the country's latest move to overhaul its health care system and expand access to better-quality and cheaper drugs. Read More

Agenus launches BEST: A crypto token for drugs

Blockchain has already infiltrated the drug industry, from tracking supply chain to information management system to cryptocurrencies to pay people for their genomic sequencing. But now Agenus Inc. is looking to use the tracking technology to help fund drug development. The company announced plans to launch a Biotech Electronic Security Token (BEST), which will be tied to its anti-PD-1 antibody, AGEN-2034. Read More

ISAL overcome: Findings from Agios in AML could boost first-line promise

During 2017 and 2018, the FDA put life aplenty into the AML space by taking action to clear or reapprove no fewer than eight drugs for acute myeloid leukemia (AML), including Agios Pharmaceuticals Inc.'s Tibsovo (ivosidenib) to treat relapsed or refractory disease with an isocitrate dehydrogenase 1 (IDH1) mutation who are not eligible for standard therapy and Idhifa (enasidenib), cleared for patients with IDH2 mutations. And the indication only looks to grow hotter. Read More

Voyager shares vault higher as Abbvie options Parkinson's candidates for $1.54B

Energized by the opening of a second front in a high-stakes gene therapy collaboration with Abbvie Inc., investors in Voyager Therapeutics Inc. lifted company shares (NASDAQ:VYGR) 22.9 percent to $13.12 Friday. Under terms of the deal, Voyager's second in Parkinson's disease (PD) in as many months, Abbvie will pay the company $65 million up front in exchange for an exclusive option to license vectorized antibodies targeting misfolded alpha-synuclein proteins for synucleinopathies, like PD. Voyager will foot the bill for developing and testing the compounds through phase I. Read More

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