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Home » Newsletters » BioWorld

BioWorld

Jan. 22, 2020

View Archived Issues
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Born again: Neurotrope back in the game with bryostatin-1 in Alzheimer’s

It was a trifecta to remember for Neurotrope Inc. on Wednesday as the company cast revealing light on a seemingly failed clinical program involving its lead candidate, had the NIH offer a grant to create a phase II trial to explore the program’s strengths, and then found institutional investors and individuals to pony up an $18 million registered direct offering for the company’s securities. It was a re-examination of data that resurrected Neurotrope’s hopes for its lead candidate months after a confirmatory phase II of bryostatin-1 failed to outperform a placebo in people with moderately severe to severe Alzheimer’s disease (AD) in the absence of Namenda (memantine, Allergan plc), an NMDA receptor antagonist. Read More
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WHO needs more information on novel coronavirus infection before declaring emergency

LONDON – The World Health Organization held off declaring the novel coronavirus infection that has emerged in Wuhan, China, an international public health emergency, despite the fact that the number of confirmed cases tripled in the past week and the infection has spread to several other countries, including the U.S. Read More
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Significant year of growth for regenerative medicine sector

According to Janet Lambert, CEO of the Alliance for Regenerative Medicine (ARM), in her delivery of the international advocacy group’s state of the industry briefing at Biotech Showcase in San Francisco, 2019 proved to be a significant year of growth for the regenerative medicine sector. Read More

PDC*Line Pharma pulls in $22M in equity, grants for lung cancer immunotherapy

PDC*Line Pharma SA raised €13.9 million (US$15.4 million) in a series B round plus another €6.1 million in loans and grants from the Walloon region of Belgium to take its allogeneic cell-based cancer immunotherapy, PDC*lung-01, into a phase I/II trial in patients with metastatic lung cancer. Read More
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Kintai’s good PEMmanship draws gutsy map to obesity and more

Kintai Therapeutics Inc. CEO, president and board member Paul-Peter Tak told BioWorld that the company aims to reach the clinic in the first quarter of next year with obesity agent KTX-0200, which has begun IND-enabling studies after showing sustained weight loss and improved markers of health in preclinical experiments. Read More
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Tennor’s prosthetic joint infections therapy, TNP-2092, set to start phase III soon

BEIJING – With promising phase II data in hand – and newly designated FDA orphan drug status – Suzhou, China-based Tennor Therapeutics Suzhou Co. Ltd. is gearing up to move into pivotal testing with TNP-2092 to treat prosthetic joint infections. Read More
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Thiel calls for improving research grant, regulatory processes to enhance scientific innovation

SANTA CLARA, Calif. – Peter Thiel is not a fan of incremental science. The high-profile venture capital investor, who invests across technology and the life sciences via various vehicles, including the Founders Fund, suggested that as academic and government bureaucracies have scaled up and rigidified over the last 50 or 60 years, that has eroded the ability of researchers to pursue innovative science. Read More
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Verily highlights diabetes care, Project Baseline even as related partnerships are restructured

SANTA CLARA, Calif. – Diabetes seems likely to be the first area to really show concrete products and results for the ambitious Verily Life Sciences, which is the med-tech business of Mountain View, Calif.-based Google parent Alphabet Inc. However, its two major diabetes partners both have been rethinking the relationship. Read More

Appointments and advancements for Jan. 22, 2020

New hires and promotions in the biopharma industry: Cohbar, Dermavant, Impel, Oncosec Read More

Earnings for Jan. 22, 2020

Quarterly snapshots from biopharma companies with marketed products: Genmab, Johnson & Johnson Read More

Financings for Jan. 22, 2020

Biopharmas raising money in public or private financings: Adaptimmune, Applied Therapeutics, Chi-Med, Cidara, Heat, Immuneering, Nanoviricides, Zai Lab, Zymeworks Read More

In the clinic for Jan. 22, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Axsome, Cytodyn, LB Pharmaceuticals, Metacrine, Moberg, Neurotrope, Vaxart Read More

Other news to note for Jan. 22, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allergan, Apexian, Astrazeneca, Axim, Basilea, Bavarian Nordic, Biocartis, Celavie, Genialis, Inotrem, Ironwood, Jazz, Ocuphire, Oncologie, Pharmacyte, Pharmamar, Proteostasis, Roche, Sapphire, Sarepta, Sierra, Zhittya Genesis Read More

Regulatory actions for Jan. 22, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Aruvant, Baudax Bio, Celularity, Genprex, Inhibitor, Jazz, Ra, Supernus Read More

Regulatory front for Jan. 22, 2020

The latest global regulatory news, changes and updates affecting biopharma: Aegerion Pharmaceuticals Inc., Alexion Pharmaceuticals Inc., Insys Therapeutics Inc. Read More

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