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BioWorld - Sunday, March 29, 2026
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Home » Born again: Neurotrope back in the game with bryostatin-1 in Alzheimer’s
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Born again: Neurotrope back in the game with bryostatin-1 in Alzheimer’s

Jan. 22, 2020
By Lee Landenberger
It was a trifecta to remember for Neurotrope Inc. on Wednesday as the company cast revealing light on a seemingly failed clinical program involving its lead candidate, had the NIH offer a grant to create a phase II trial to explore the program’s strengths, and then found institutional investors and individuals to pony up an $18 million registered direct offering for the company’s securities. It was a re-examination of data that resurrected Neurotrope’s hopes for its lead candidate months after a confirmatory phase II of bryostatin-1 failed to outperform a placebo in people with moderately severe to severe Alzheimer’s disease (AD) in the absence of Namenda (memantine, Allergan plc), an NMDA receptor antagonist.
BioWorld Clinical Financings Neurology/psychiatric

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