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Quantification of blood flow through major blood vessels is not an easy process – and may have to resort to invasive techniques rather than just imaging. But researchers working as part of the Quantitative Imaging Biomarkers Alliance (QIBA) have recently validated an open-source algorithm that can be used to measure blood flow using existing 3D ultrasound technology from major manufacturers. They published their results in the June 30, 2020, issue of Radiology.
Strongly positive histological data from Akero Therapeutics Inc. is being seen as setting a potentially new high bar in treating nonalcoholic steatohepatitis (NASH), but 89bio Inc.’s NASH treatment, on a similar development timeline, is sharing in the success.
LONDON – Biontech SE announced positive preliminary data from the ongoing phase I/II trial of one of the four COVID-19 vaccines it is developing with Pfizer Inc., with participants in each of three dose groups mounting immune responses that were greater than seen in patients who recovered from COVID-19 infections. The two companies said they are on track to begin a phase IIb/III study involving up to 30,000 healthy volunteers before the end of July, and if successful, expect to manufacture 100 million doses by the end of 2020 and potentially more than 1.2 billion doses by the end of 2021.
