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Home » Newsletters » BioWorld

BioWorld

April 28, 2023

View Archived Issues
FDA icons and doctor

No PARPing zone: FDA adcom recommends restricting Lynparza in treating prostate cancer

The U.S. FDA’s Oncologic Drugs Advisory Committee has recommended by a wide majority that the PARP inhibitor Lynparza (olaparib) in a combination therapy for treating prostate cancer should be restricted to only patients whose tumors have a BRCA mutation. Read More
Green approved stamp

BMS’s heart drug, two biologics among latest EU approval recommendations

A heart-protective cardiac myosin inhibitor and two biologics – one for a type of non-Hodgkin lymphoma and another for an inflammatory skin condition – were among the therapies recommended for approval by the EMA’s Committee for Medicinal Products for Human Use this week. Read More
Daewoong_4-28.jpg

Vitalli Bio launches with $477M licensing deal with Daewoong for phase I-ready autoimmune disease candidate

Daewoong Pharmaceutical Co. Ltd. has out-licensed its phase I-ready autoimmune disease candidate, DWP-213388, to new spinout company Vitalli Bio in a deal worth up to $477 million. Read More

Top 4D? Phase I gene therapy data in wet AMD climb chart; Adverum, Regenxbio also in play

Touting what’s been so far the “cleanest safety profile that’s been presented with genetic medicine in the eye,” deemed “a game changer for this field,” 4D Molecular Therapeutics Inc. CEO David Kirn said phase III planning will begin in later this year to test gene therapy 4D-150 in wet age-related macular degeneration (AMD). Read More
Illustration of animals, DNA double helix

In Zoonomia project, evolutionary lens hones search for functional genomic variants

A base-by-base comparison of the genome sequences of 240 species of mammals has pinpointed sites in the human genome where mutations are likely to cause disease. The sites are all perfectly conserved across the mammalian family tree over 100 million years of evolution, indicating they underlie fundamental biological processes that do not tolerate diversity or change very well. Read More

The BioWorld Insider Podcast: Better times ahead for the biopharma sector? Could be, the new numbers say

It used to be a lot easier to find partners. After two years of strong dealmaking, the volume and value of partnerships slid in the first quarter of 2023. M&As also are down compared to prior years. But there are some reasons to be cheerful. Looking at first quarter numbers and surveying the big picture on this BioWorld Insider podcast are Karen Carey, BioWorld’s managing editor and senior data analyst, along with Tim Shannon, a general partner at Canaan. Carey just wrote about biopharma deals and completed M&As in the first quarter. Shannon, who’s been with Canaan since 2009, has a new fund sporting $850 million in new capital, including an oversubscribed $650 million fund for seed and series A financings. They both offer their insights into the first quarter’s numbers and what may lie ahead. Read More

Appointments and advancements for April 28, 2023

New hires and promotions in the biopharma industry, including: Adagene, Antiva, Gameto, Sutro. Read More

Financings for April 28, 2023

Biopharmas raising money in public or private financings, including: Cel-Sci, Hillstream, Ideaya, Maia, Navidea, Tryp.

Read More

In the clinic for April 28, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Alligator, Alnylam, Amphera, Avacta, Biocryst, Bionomics, Celularity, Cinrx, Clearside, Elicio, Galapagos, Junshi, Lilly, Minoryx, Nexcella, Palatin, Regeneron, Skye. Read More

Other news to note for April 28, 2023

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Amgen, Openbench, Provention, Sanofi, Tavros. Read More

Regulatory actions for April 28, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Amicus, BMS, Editas, Eli Lilly, Gensight, GSK, Intelgenx, Novartis, Ocugen, Roche, Seres, Taiho, Takeda. Read More

Money raised by biopharma

Total raised in public, private and other financings of biopharma companies, comparing 2023 vs. 2022 vs. 2021 vs. 2020 vs. 2019. Read More

Biopharma money raised: Jan. 1-April 27, 2023

Year-to-date money raised in public, private and other financings of biopharma companies. Read More

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