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BioWorld Science

March 26, 1999

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Oxford GlycoSciences: 1998 highlights

Atrix: Q4 and year-end 1998 highlights

FDA grants orphan drug status to recombinant Pharming product

Benefits of single-dose therapy shown in preliminary phase II data on MiKasome

Lilly and Ribozyme to collaborate on new HCV treatment

AEterna's AE-941/Psovascar shows positive results in phase I/II trial in psoriasis

Novo Nordisk's liquid somatropin approved in Denmark

Novel antifungal agents from Pola

AstraZeneca merger gets green light from FTC; companies announce closing timetable

Orally active antidiabetic agents patented by Otsuka

Sugen's new protein tyrosine kinase inhibitors

Broad-spectrum antibacterial agents with low toxicity described by Korean scientists

Celgene synthesizes potent TNF-alpha and PDE4 inhibitors

ACS highlights: potent and selective small-molecule CXCR2 antagonists in early development at SB

Molecumetics presents small-molecule compound from NF-kB inhibitor program at ACS meeting

Asahi Chemical launches alpha-adrenoceptor antagonist in Japan

New antiasthmatic compound from Nissan Chemical improves airways smooth muscle function

Celecoxib is an effective antipyretic agent in man

ACS meeting selected by Agouron for unveiling structure of AG-7088

New addition to the Ube pipeline may treat both cognitive dysfunction and depression in AD

MS-377, a potential antipsychotic agent with affinity for sigma-receptors

Roche Bioscience drops development of heart failure Rx

Chiroscience, Zeneca finalize terms for return of Chirocaine license

Pharmacokinetics and safety of lotrafiban assessed in phase II trial

Neonatal pharmacokinetics of pleconaril differ from those in children

Na+/H+ exchange inhibitor is effective in both transient and permanent focal ischemia models

Phase II results reported for RSD-921 at ASCPT meeting

5-HT7 antagonist DR-4004 shows anxiolytic efficacy in murine model

Cognition-enhancing activity of ipidacrine is comparable to that of donepezil in preclinical model

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