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BioWorld Science

Nov. 27, 2001

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Recombinant HSP-based vaccine enters clinical testing at Antigenics for infectious disease

Highly potent, selective and orally active 5-HT1F agonist identified by Lilly and Synaptic

Collaborative computer-aided drug design program yields potent new GH secretagogues

InterMune to focus efforts on development of three late-stage development programs

Inhibition of p38 MAP kinase reduces ischemic vulnerability in transgenic mouse model

Cambridge Antibody Technology strengthens therapeutic pipeline during 2001

Small-molecule neurotrophic compound protects against cerebral ischemia

Small-molecule caspase 3 inhibitor effective against neonatal ischemia/hypoxia-induced brain damage

Novel optic nerve-regenerating growth factor identified as potential glaucoma therapeutic

Beta-sheet breaker peptide reduces both amyloid plaques and nerve cell death in model of AD

Cell Genesys and Japan Tobacco modify cancer vaccines agreement

American Biogenetic Sciences enters agreement for anthrax and smallpox vaccines

Mitochondrial permeability transition pore modulator provides cardioprotection

Matrix seeks approval for IntraDose in Europe

AstraZeneca to return development rights for ZD-0473 to AnorMED

Sheffield initiates budesonide inhalation suspension study

Alcon and Angiotech terminate ophthalmic R&D collaboration

Anti-MCP-1 gene therapy shows potential for preventing post-MI heart failure

Parker Hughes Institute continues R&D on thiophene-substituted thiourea anti-HIV agents

Antitumor and antimetastatic effects demonstrated in new series from Ishihara Sangyo

Pfizer prepares diphenyl ether inhibitors of monoamine reuptake

New peptide derivatives synthesized at Takeda as G-protein-coupled receptor ligands

Delta opioid receptor agonists and their uses described in recent patent

Schering scientists identify iNOS inhibitors

Triarylimidazole inhibitors of TGF-beta signaling pathway under study at GSK

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