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BioWorld Science

Feb. 18, 2002

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Emisphere reports on pipeline progress in 2001

Rho kinase as a target for drug discovery in Japan

Preclinical data support development of CS-758 for therapeutic use in fungal infections

Des-fluoroquinolone exerts potent activity against respiratory and genital Chlamydia

NO-flurbiprofen more effective and safer than flurbiprofen in accelerating tendon healing

Teicoplanin-loaded PLGA microspheres potentially useful in musculoskeletal infections

Novartis licenses AC-5216 from Dainippon

New antibiotic with selective activity against H. pylori

Preliminary phase IIIb results reported for transdermal oxybutynin in overactive bladder

ViroLogic technology used to evaluate Panacos HIV drug candidates

Phytomedics and Eisai collaborate to discover cancer therapeutics

Positive preclinical and clinical results for NCX-1015 in IBD and arthritis

Hollis-Eden signs CRADA for joint development of HE-2100 for radiation damage

Tranzyme and Gemin X enter neurological drug discovery collaboration

COLAL-PRED enters late-stage trials for ulcerative colitis

OP-1 Implant receives Canadian approval

NeoGenesis and Aventis collaborate on infectious disease drug discovery

F-12511 reduces hypercholesterolemia and progression of atherosclerotic lesions in rabbit model

Initiation of phase III trial of secretin in autism; further data analysis from phase II trial

Mutant heat-labile enterotoxin as a potent adjuvant for oral influenza vaccination

Results from the TIMI-8 trial confirm unique risk/benefit profile of bivalirudin

Taisho claims compounds that inhibit the production of 20-HETE

Compounds that enhance transcription factor AP-1 designed at Active Biotech

Cyclopentyl carboxamides with potential in female sexual dysfunction

Merck claims preparation of macrocyclic compounds for treatment of cancer, etc.

Abbott/Ligand jointly identify selective glucocorticoid modulators

Ortho-McNeil identifies nonpeptide vasopressin receptor antagonists

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