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BioWorld Science

April 11, 2002

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Nymox collaborates with Brown on cancer therapeutics and diagnostics

PPL presents roundup of key developments last year

Axokine phase III program expanded with two new studies

New orally active taxane, DJ-927, with a promising preclinical profile

NVP-LAF-389 induces amino-terminus changes in cytosolic protein indicative of enzyme inhibition

Proof of principle demonstrated for Corixa's duocarmycin/tumor-activated prodrug approach

New antimitotic indole-oxazoline derivative exhibits antivascular and proapoptotic effects

Small-molecule antimitotic agents a focus of cancer research at Abbott

CP-547632, a new oral VEGFR-2 tyrosine kinase inhibitor, advances to studies in humans

SAR on a series of group I metabotropic glutamate receptor antagonists reported at ACS meeting

Enrollment complete in second phase II trial of pexelizumab in acute myocardial infarction

Rhein Biotech licenses RC-529 for use in hepatitis B vaccines

Clinical update for GCS-100 (GBC-590) provided by GlycoGenesys

Roche to codevelop ISAtx-247 with Isotechnika

Ro-098246: a new triazole antifungal agent with improved potency and spectrum

Xanelim enters phase II trial in moderate to severe rheumatoid arthritis

E.U. submission for Arimidex in early-stage breast cancer in postmenopausal women

ACS news: design of new Zn2+-dependent inhibitor of HCV NS3 serine protease

Estradot launched in Germany for menopausal symptoms

Oratonin enters clinical testing for osteoporosis

Benzimidazoles and analogues claimed for treatment of inflammatory diseases

Eisai claims 2-aminopyridines with adenosine receptor-antagonist activity

Gepirone metabolite useful as antidepressant according to recent patent

New series of protein kinase inhibitors prepared at GSK

Scientists at AstraZeneca present new VEGF inhibitors and potential uses

Hypolipidemic agents acting via inhibition of apo B secretion described by Tanabe

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