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BioWorld Science

Oct. 23, 2002

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Research milestone in delivery of gene vector to muscle cells for Duchenne muscular dystrophy

Two series of GnRH antagonists presented by AstraZeneca researchers

ChemBridge applies GPCR-targeted library to discover small molecule agonist

Forest receives approvable letter for oxycodone hydrochloride/ibuprofen

Another series of ALK5 inhibitors described by GSK researchers

Procyon and Chiron will not extend license option agreement for recombinant PSP94

Merckle claims novel compounds with cytokine-modulatory activity

DOR BioPharma options intellectual property for antiinflammatory drugs for IBS

New factor VIIa inhibitors in early development at Chugai

Bristol-Myers Squibb describes novel retinoid agonists for cancer and other disorders

Novel beta2-adrenoceptor agonists for use as bronchodilators claimed by GSK

Epimmune and Genencor extend collaboration for HCV, HBV and HPV vaccines

Compounds with dual 5-HT reuptake and alpha2-adrenoceptor-inhibitory activity under study at Janssen

Subcutaneous alemtuzumab reported to be safe and effective for B-CLL

Delivery of the D1 agonist ABT-431 with the AERx pulmonary delivery system

Paroxetine reported to improve response to high-fiber diet in IBS patients

Coherin may be useful for inducing and maintaining remission in ulcerative colitis

High-dose ISIS-2302 safe and effective in Crohn's disease

Resolution of steatosis with pioglitazone

Improved GERD symptoms following treatment with Enteryx

Phosphodiester oligonucleotide has potential for treatment of CML according to preclinical data

Evidence that coenzyme Q10 slows functional decline in PD

European CPMP recommends approval of Caelyx for metastatic breast cancer

Celgene advances first JNK inhibitor into clinic

Banyu and Pharmacia sign development and commercialization agreement for J-107088

FDA accepts Striant NDA for review

Top-line results from phase IIb/III sitaxsentan trial

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