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BioWorld Science

March 28, 2017

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Regenxbio initiates phase I trial of gene therapy RGX-314 for wet AMD

Phase II trial of XEN-801 for acne does not meet efficacy endpoints

BARDA elects not to exercise options for AEOL-10150 development for ARS and DEARE

Xeljanz approved in Europe

AbbVie begins first-in-human trial of ABBV-621

Dacomitinib shows efficacy against penile squamous cell carcinoma

Levosimendan does not result in lower 30-day mortality in high risk cardiac surgery patients

KPR-2579, a novel TRPM8 antagonist for the potential treatment of bladder hypersensitivity

Erytech and Fox Chase to advance preclinical development of erymethionase for homocystinuria

Initiation of phase II trial of LN-145 in patients with squamous cell carcinoma of the head and neck

Epicentre presents phase III efficacy and safety results for oral BRV-PV rotavirus vaccine

Matinas reports topline phase I data on MAT-2501

Synergy submits supplemental NDA for Trulance in IBS-C

Numab and Ono Pharmaceutical enter immuno-oncology research and option agreement

Oncology Venture to evaluate Eisai drug for potential in-licensing

Amryt initiates phase III trial of AP-101 for epidermolysis bullosa

FDA approves Zejula for the maintenance treatment of women with recurrent ovarian cancer

ImMAGE Biotherapeutics advances immunotherapy for triple-negative breast cancer

Infectex reports results from phase IIb/III trial of SQ-109 for multidrug-resistant pulmonary TB

Sumitomo Dainippon Pharma presents Nav1.7 channel blockers

F. Hoffmann-La Roche AG patents gamma-secretase inhibitors

FDA grants priority review to Ryanodex NDA to treat exertional heat stroke

Genentech and F. Hoffmann-La Roche AG divulge PI3Kalpha inhibitors

European Commission gives conditional approval to DuPont and Dow Chemical Company's merger of equals

Vaximm updates on lead compound VXM-01 at BIO-Europe Spring

Foamix reports phase III topline results for FMX-101 in moderate to severe acne

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