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BioWorld Science

Feb. 14, 2019

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Making chemo worse for cancer, better for heart

Making jumping genes sit still could be antiaging strategy

Exelixis begins phase I development with tyrosine kinase inhibitor XL-092

Kodiak Sciences looks to phase II with KSI-301 for retinal diseases

Phase I results demonstrate clinical proof of mechanism for SJX-653

Alphabet soup: multiple pancreatic cell types can be reprogrammed into 'pseudoislets'

Enrollment ongoing in phase I study of NUC-7738 in patients with advanced solid tumors or lymphoma

Affinivax initiates phase I/II study ASP-3772

Catalyst Biosciences presents data from MAA-201 study of MarzAA

Phase I safety and pharmacokinetics data presented for LCB01-0371

Researchers present novel vaginal rings designed for sustained delivery of 5P12-RANTES

DNA-based Mayaro virus vaccine protects mice from virus challenge

Discovery of VU-2957, a novel metabotropic glutamate mGlu4 receptor PAM

Cyclin D1 deficiency in SCCOHT confers high susceptibility to CDK4/6 inhibitors

ARHGEF1 loss found to cause a type of primary antibody deficiency

Nimbus Lakshmi discloses new TYK2 inhibitors

Jiangsu Hengrui Medicine, Shanghai Hengrui Pharmaceutical patent HBV capsid assembly inhibitors

FDA approves Egaten for fascioliasis

Sanofi discovers antimycobacterial compounds

Abilita Bio enters into multitarget research collaboration agreement with Amgen

Chengdu Di'ao Pharmaceutical Group presents new proteasome inhibitors

Caladrius reports 1-year data from phase IIa trial of CLBS-03 in recent onset type 1 diabetes

Hepagene Therapeutics identifies inhibitor of apoptosis proteins (IAP) inhibitors

FDA issues complete response letter for iclaprim NDA in ABSSSI

Addex and Indivior intend to accelerate additional GABA-B PAM compounds for addiction

FDA clears IND for phase II study of LPCN-1144 in biopsy-confirmed NASH

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