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BioWorld - Wednesday, June 7, 2023

Ocular

Home » Topics » Disease categories and therapies » Ocular
  • June 6, 2023
    By Cormac Sheridan

    AAVantgarde Bio secures $65M series A round for large gene delivery in AAV vectors

    AAVantgarde Bio SrL raised €61 million (US$65 million) in series A funding to take forward two novel approaches to gene therapy that aim to overcome the packaging limits of adeno-associated virus (AAV) vectors. The company plans to move its lead program, in retinitis pigmentosa associated with Usher syndrome type 1b, into the clinic later this year. A second program, in Stargardt disease, is a couple of years behind it.
  • Eye anatomy illustration
    June 1, 2023

    IL-17A as a new therapeutic target in glaucoma

    It has been previously demonstrated that IL-17A plays a proinflammatory role in autoimmune diseases, and it has also been reported that IL-17A may take part in the occurrence and development of neurodegenerative disorders. Due to its association with both immunomodulation and inflammation, in a recent study, researchers from Shanghai Jiao Tong University aimed to investigate the role of IL-17A in the pathological process of glaucoma neuropathy.
  • Eye and dna
    May 31, 2023
    By Cormac Sheridan

    Signs of efficacy seen in Coave's gene therapy trial in RP

    Coave Therapeutics aims to move its lead gene therapy program, CTx-PDE6b, for a form of retinitis pigmentosa (RP) into a pivotal trial in 2025 on the back of a phase I/II study, which uncovered a preliminary efficacy signal in one patient subgroup.
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  • Randy Osborne
  • Mark McCarty
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