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BioWorld - Friday, February 26, 2021

Ocular

Home » Topics » Disease categories and therapies » Ocular
  • Feb. 2, 2021
    By Randy Osborne

    Ascend to know why bell tolls for Immunovant; lipid-hitch delay, but 1401 not Donne

    Less than a month after informing the market of a slowdown caused by pandemic-related site closures in phase II studies with neonatal Fc receptor (FcRn)-targeting IMVT-1401, Immunovant Inc. said it’s voluntarily pausing dosing with the compound in thyroid eye disease (TED) in the study called Ascend Go-2 because of a worrisome physiological signal. The New York-based firm plans to investigate and, after seeking the FDA’s go-ahead on tweaks to the program, forge onward with development.
  • Eye genetics
    Jan. 19, 2021
    By John Fox

    HELP is on its way for herpetic stromal keratitis

    Transient gene editing of the herpes simplex virus type 1 using mRNA-based CRISPR was shown for the first time to be effective against herpetic stromal keratitis in mice and blocked HSV-1 replication in human corneas, Chinese researchers reported in the January 11, 2021, online edition of Nature Biotechnology.
  • 12 10 georgia tech ocular needle with eye
    Dec. 10, 2020
    By Annette Boyle

    Georgia Tech envisions new glaucoma treatment with hydrogel injections

    Researchers at the Georgia Institute of Technology see a future where long-lasting hydrogel injections replace eye drops and surgery in the management of glaucoma, the most common cause of irreversible blindness in the world. The treatment would be delivered every six months, in line with glaucoma patients’ regularly scheduled visits to the ophthalmologist.
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Authors

  • Randy Osborne
  • Mark McCarty
  • Michael Fitzhugh
  • Meg Bryant
  • Tamra Sami
  • Lee Landenberger
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