Total: $334.89M

Company (Symbol)#

Type Of Financing

Number Of Shares, Units Or Warrants (M)

Amount Raised (M)

Investors; Placement Agents; Details (Date)@


Acusphere Inc. (ACUS)

Private placement of stock and warrants

2.9S and
0.574W

$17.9

Acusphere sold the shares at $6.25 each, and the warrants are exercisable at $8.50 per share; it expects to complete a second closing of $3.6M later in 2004; SG Cowen & Co. LLC was placement agent (8/2)

AspenBio Inc. (OTC BB: APNB)

Private placement of units

N/A

$1.29

In a second closing, AspenBio sold units consisting of 20,000 common shares and 20,000 warrants exercisable for three years at $1.50 per share; the units were sold at $17,500 each (8/19)

BioDelivery Sciences International (BDSI)

Credit facility

N/A

$4

BDSI gained access to $4M from an affiliated entity, Hopkins Capital Group II; the debt would mature in March 2006, after which HCG II could convert the debt into stock at $4.25 per share (8/3)

BioPhage Pharma Inc. (Canada; VSE:BUG)

Private placement of units

5.31S and
1.59W

C$0.552

(US$0.42)

Each of the 5.31M units, which were sold at C$0.104 each, consists of one share and 0.30 of a warrant; each whole warrant allows the purchase of a common share at C$0.25 each for two years; Carpe DM Inc. provided some contacts in the deal (8/2)

ChondroGene Ltd. (Canada; TSE:CDG)

Private placement of stock and warrants

5.263S and
0.316W

$5

The shares were placed at $0.95 each; placement agent Rodman & Renshaw got a 6% fee and a two-year warrant to purchase 315,790 shares at the same price (8/25)

Eiffel Technologies Ltd. (Australia; ASX:EIF)

Private placement of stock

36.4S

A$3

(US$2.14)

Eiffel placed the shares at A$0.825 each; sales of about 8.6M of the shares are subject to share-holder approval; Intersuisse Corporate managed the placement (8/06)

Hemispherx Biopharma Inc. (AMEX:HEB)

Private placement of stock and warrants

3.6S and
1.085W

$7.5

Units in the financing were sold at $2.08 each; the five-year warrants are exercisable at $2.86 per share (8/2)

Hybridon Inc. (AMEX:HBY)

Private placement of stock and warrants

8.8S and
1.8W

$5.1

Hybridon sold the shares at $0.58 each to institutional and overseas investors; Great Point Partners LLP and Optima Life Sciences Ltd. bought most of the shares; the warrants are convertible into shares at $0.67 each (8/30)

Immunomedics Inc. (IMMU)

Private placement of stock and warrants

4.18S and
4.18W

$15.1

The shares were sold from a shelf registration at $3.61 each; warrants are convertible into shares at $3.97 each no later than Nov. 24, 2004; RBC Capital Markets was placement agent (8/2)

ISTA Pharmaceuticals Inc. (ISTA)

Private placement of stock

1.57S

$13.3

The shares were sold from a shelf registration to institutional investors at $8.50 each; Banc of America Securities LLC, Thomas Weisel Partners LLC, Lazard Freres & Co. LLC and C.E. Unterberg, Towbin LLC were placement agents (8/6)

MediGene AG (Germany; FSE:MDG)

Private placement of securities

ND

€4
(US$4.9)

Concurrent with MediGene's acquisition of Munich Biotech AG, Munich Biotech shareholders invested €4M in MediGene (8/13)

Mologen AG (Germany; FSE:MGNG)

Private placement of stock

0.511S

€0.818
(US$0.99)

Ahead GmbH purchased the shares at a discount of 5% to the 10-day average price, and now owns 9.1% of Mologen (8/26)

Neuropharma (subsidiary of Zeltia SA; Spain; MSE:ZEL)

Private placement of stock

2.06S

€16
(US$19.3)

Investors purchased 25% of the subsidiary; prior to the deal Zeltia owned 100% of Neuropharma; Banco Banif structured the deal (8/2)

Neutec Pharma plc (UK; LSE:NTP)

Open offer and placement

5.28S

£25.8
(US$47)

Applications were received for about 31.4% of the shares in the open offer; the offer was fully under-written by Hoare Govett Ltd. (8/12)

Pharmos Corp. (PARS)

Private placement of stock

5.58S

$16.75

The shares, covered under a shelf registration, were sold to institutional investors at $3 each; Rodman & Renshaw Inc. and Harris Nesbitt were co-lead placement agents (8/23)

Pro-Pharmaceuticals Inc. (AMEX:PRW)

Private placement of stock and warrants

2S and
2W

$6

The shares were sold at $3 each to new and existing institutional investors; the five-year warrants are convertible at $4.20 per share; Rodman & Renshaw was placement agent (8/12)

Protherics plc (UK; LSE:PTI)

Open offer and placement

20.77S

£10
(US$18.2)

Shareholder purchased about 53% of the shares in the open offer, while the remainder were placed with institutions (8/11)

Qiagen NV (the Netherlands; QGENF)

Private placement of convertible notes

N/A

$150

The senior unsubordinated convertible notes due 2024 were offered with a coupon of 1.5% and are convertible into common shares at $12.645 per share; purchasers have an option to buy another $22.5M in notes (8/4)


Notes:

This chart does not include real estate or manufacturing plant financings.

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

@ Dates refer to the date of the press release.

Currency conversions are based on exchange rates at the time of the deal.

N/A = Not applicable; ND = Not disclosed.

AMEX = American Stock Exchange; ASX = Australian Stock Exchange; FSE = Frankfurt Stock Exchange; LSE = London Stock Exchange; MSE = Madrid Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSE = Toronto Stock Exchange; VSE = Vancouver Stock Exchange.