Total: $718.97M

Company (Symbol)#

Type Of Financing

Number Of Shares, Units Or Warrants (M)

Amount Raised (M)

Investors; Placement Agents; Details (Date)@


Aastrom Biosciences Inc. (ASTM)

Private placement of stock and warrants

8S and 2.4W

$9.1

Aastrom placed the shares with institutional investors at about $1.14 per share; the warrants are exercisable for five years at $1.65 per share; Jesup & Lamont Securities Corp. was placement agent (4/5)

Acacia Research Corp. (CBMX)

Registered direct offering

3S

$15

Institutional investors purchased the Acacia Research-CombiMatrix Group stock that is covered under an effective registration statement; Thomas Weisel Partners LLC was lead placement agent and Brean Murray & Co. was co-placement agent (4/14)

Adventrx Pharmaceuticals Inc. (OTC BB:AVRX)

Private placement of stock and warrants

10S and 3W

$15

Adventrx sold the shares at $1.50 each, and the five-year warrants are exercisable at $2.50 per share; Burnham Hill Partners was placement agent (4/5)

Amylin Pharmaceuticals Inc. (AMLN)

Private placement of convertible notes

N/A

$25

Purchasers of $175M of 2.5% convertible senior notes due 2011, initially convertible at $34.35 per share, exercised their option on another $25M in notes; the initial purchase was in March (4/5)

Bioxel Pharma Inc. (Canada; TSE:BIP)

Loan

N/A

C$2.5
(US$1.88)

Bioxel reached a preliminary agreement for the loan from Investissement Québec under the BioLevier program (4/6)

Callisto Pharmaceuticals Inc. (OTC BB:CLSP)

Private placement of stock

2.15S

$4.84

Callisto sold the shares at $2.25 each in a placement managed by Punk Ziegel & Co. (4/19)

Cytogen Corp. (CYTO)

Direct sale of registered shares

2.57S

$26

Cytogen sold the shares from a shelf registration at $11.10 each; CIBC World Markets Corp. was lead placement agent; JMP Securities LLC and ThinkEquity Partners LLC were co-placement agents (4/15)

Cytomedix Inc. (OTC BB: CYME)

Private placement of securities

ND

$4.5

Cytomedix raised $4.5M in a private placement, three days after it brought in $2.8M through the sale of preferred stock and warrants; details on this deal were not disclosed (4/1)

DeCode Genetics Inc. (Iceland; DCGN)

Private placement of convertible notes

N/A

$150

The senior convertible notes are due 2011 and carry an interest rate of 3.5%; they will be convertible into common shares at $14 per share, a 35% premium at the time of the deal; the totals include $25M in notes purchased as an overallotment option (4/7)

DUSA Pharmaceuticals Inc. (DUSA)

Private placement of stock

0.3375S

$3.71

Investors in a financing in February exercised their option on another 337,500 shares; in total the financing raised about $28.5M (4/15)

Epimmune Inc. (EPMN)

Private placement of stock and warrants

2.47S and 1.23W

$5.5

The shares and warrants were sold as a unit at $2.2125 per unit; the warrants are exercisable at $2.655 per share; Jefferies & Co. Inc. was financial adviser and placement agent (4/13)

GeneMedix plc (UK; LSE:GMX)

Private placement of stock

13.45S

£1.9
(US$3.36)

GeneMedix placed the shares, which were priced at a 10% discount, mostly with Asian investors (4/15)

GenVec Inc. (GNVC)

Private placement of

4S

$12.6

GenVec sold the shares from a shelf registration statement to institutional investors at $3.15 per share; Stonegate Securities Inc. was placement agent (4/16)

Hybridon Inc. (AMEX:HBY)

Private placement of stock and warrants

16.9S and 3W

$11.8

The shares are being sold from a shelf registration statement; the warrants can be exercised at $1.14 per share between Oct. 21, 2004, and April 20, 2009; Thomas Weisel Partners LLC, Rodman & Renshaw LLC and Merriman Curhan Ford & Co. are placement agents (4/16)

Imcor Pharmaceutical Co. (ICPHC; formerly Photogen Technologies Inc.)

Private placement of stock and warrants

13.33S and 3.33W

$10

Imcor got binding commitments for the sale, which entails shares sold at $0.75 each that include one-half a warrant; each whole warrant is exercisable for five years at $1 per share; the first tranche of the deal includes 2.65M shares; the remainder would come after shareholder approval (4/14)

Incara Pharmaceuticals Corp. (OTC BB:ICRA)

Private placement of stock and warrants

41.04S and 16.4W

$10.26

The shares were sold at $0.25 each and the five-year warrants are exercisable at $0.40 per share; investors included Biotechnology Value Fund, Perceptive Life Sciences and Great Point Partners; SCO Securities LLC was placement agent (4/19)

Integrated BioPharma Inc. (AMEX:INB)

Private placement of convertible preferred stock and warrants

0.0085S and 0.425W

$8.5

The Series B redeemable preferred stock, priced at $10,000 per share, is convertible into common stock at $10 per share; the shares pay a dividend of 7% per year and are redeemable after three years; the five-year warrants are exercisable at $14 per share; investors also got the right to purchase additional preferred stock and warrants, together convertible into 637,500 shares, with the same terms (4/21)

Medarex Inc. (MEDX)

Private placement of convertible senior notes

N/A

$150

The 2.25% notes due 2011 are convertible at about $13.72 per common share, a 30% premium to the April 27 price; investors have an option to purchase up to $50M more in notes (4/28)

Miravant Medical Technologies Inc. (OTC BB:MRVT)

Private placement of stock

4.564S

$10.27

Miravant sold the stock to institutional investors; there were no placement fees associated with the deal (4/27)

Nanogen Inc.

Private placement of stock

0.9S

$7.7

Nanogen sold the shares from a shelf registration (NGEN) statement to institutional investors at $8.60 per share; Seven Hills Partners LLC acted was placement agent (4/7)

Northfield Laboratories Inc. (NFLD)

Registered direct offering

0.409S

$2.3

Investors in a financing in January exercised their option to purchase another 409,483 shares; the offering totaled about $18.7M (4/15)

Prana Biotechnology Ltd. (Australia; PRAN)

Private placement of ADRs and warrants

4S and 3W

$20

Prana placed the American depository receipts with institutional investors; the five-year warrants are exercisable at $8 per ADR; investors included OrbiMed Advisors and Xmark Funds; Rodman & Renshaw LLC was placement agent (4/28)

Pro-Pharmaceuticals Inc. (AMEX:PRW)

Private placement of stock and warrants

1.25S and 0.625W

$4.5

Terms of the sale to institutional investors were not disclosed; Rodman & Renshaw LLC was placement agent (4/7)

Sirna Therapeutics Inc. (RNAI)

Private placement of stock

5.538S

$18

Sirna agreed to sell at least $18M in stock at $3.25 per share in a deal with institutional investors (4/30)

SkyePharma plc (UK; SKYE)

Private placement of convertible notes

N/A

£20
(US$35.8)

The 6% bonds have a first put after five years with a final maturity of 2024; they are convertible into stock at a premium of 65% to the April 29 share price (4/29)

Spectrum Pharmaceuticals Inc. (SPPI)

Private placement of stock and warrants

3.2S and 1.1W

$24.8

Spectrum sold the shares at $7.75 each, and the warrants are exercisable at $10 per share starting in April 2005 (4/21)

The Immune Response Corp. (IMNR)

Private placement of stock and warrants

6.857S and 2.057W

$12

Immune Response sold the shares to institutional investors at $1.75 each; the five-year warrants are convertible into common stock at $2.75 per share; Rodman & Renshaw LLC was placement agent (4/30)

Transkaryotic Therapies Inc. (TKTX)

Private placement of convertible notes

N/A

$90

underwriters have an overallotment option on another $10M in notes; co-lead managers were JP Morgan Securities Inc. and SG Cowen & Co. LLC; co-managers were Pacific Growth Equities LLC and RBC Capital Markets Corp. (4/28)

Viragen Inc. (AMEX:VRA)

Private placement of notes and warrants

ND

$20

Viragen entered agreements with institutional investors for the sale of $20M in convertible promissory notes and common stock purchase warrants; the deal is contingent on various approvals from stockholders (4/5)

ViRexx Medical Corp. (Canada; TSE:VIR)

Offering of units

11U

C$8.8
(US$6.55)

ViRexx sold 11M units, each consisting of one share and half a warrant; each whole warrant entitles the holder to purchase one share at C$1 until Oct. 14, 2005; the totals include the exercise of the overallotment option by Canaccord Capital, the exclusive agent for the offering (4/15)


Notes:

This chart does not include real estate or manufacturing plant financings.

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

@ Dates refer to the date of the press release.

Currency conversions are based on exchange rates at the time of the deal.

N/A = Not applicable; ND = Not disclosed.

AMEX = American Stock Exchange; LSE = London Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSE = Toronto Stock Exchange.