Company*
(Symbol)

Product

Description

Indication

Status (Date)


CARDIOVASCULAR

Forbes Medi-
Tech Inc.
(Canada;
FMTI
TSE:FMI)

FM-VP4

Cholesterol-lowering pharmaceutical

High cholesterol

Company received approval to start a Phase I/II trial in the Netherlands (9/24)

INFECTION

Genelabs
Technol-
ogies Inc.
(GNLB)

¿

Vaccine

For prevention of disease caused by the hepatitis E virus

Company started a Phase II trial in Nepal (9/25)

Hollis-Eden
Pharmaceu-
ticals
Inc.
(HEPH)

HE2000

Immune-regulating hormone

HIV

Clinical results showed the drug had a significant effect on multiple genes implicated in inflammation and immune suppression associated with HIV progression to AIDS; the study was conducted in South Africa (9/10)

Tripep AB
(Sweden)*

GPG

Treatment for HIV

HIV

Phase II results were negative, causing the company to cancel the clinical program (9/17)

MISCELLANEOUS

Alizyme plc
(UK; LSE:
AZM)

ATL-
1251

5-HT4 receptor agonist/5-HT3 receptor antagonist

Constipation-predominant irritable bowel syndrome

Company received approval to start a Phase IIb trial in the UK (9/19**)

Cellegy
Pharma-
ceuticals
Inc.
(CLGY)

Rectogesic

Nitroglycerin
ointment

Anal fissures

Company submitted a marketing authorization application in the UK (9/5)

Immtech
International
Inc.
(IMMT)

DB289

Oral, anti-infective

African sleeping sickness (trypanosomiasis)

Company began a Phase II study in Angola (9/11)

QLT Inc.
(Canada;
QLTI) and
Novartis
Ophthalmics

Visudyne

Verteporfin for injection

Occult subfoveal choroidal neovascularization

Companies filed for approval in Europe (9/7); companies filed for approval in Canada (9/10)


Notes:

* Privately held; ** Denotes the date the item ran in BioWorld International.

Unless otherwise noted, the stock symbols listed for public companies are on the Nasdaq market.

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