MIXED BAG FOR TRADERSBioscience shares were mixed on Monday, with the AMEXBiotechnology Index gaining for a second session to 146.17, up2.92 points.

Xoma Corp. (NASDAQ:XOMA) was the most active biotech stock,losing 25 cents to $17.63 on more than 1 million shares traded.Rival Centocor Inc. also fell 25 cents to $11.75 on more than700,000 shares traded.

Alliance Pharmaceutical Corp. (NASDAQ:ALLP) rebounded $1.63to $18.88 after falling $2 on Friday. More than 1 million shareshave traded in the past two sessions.

Interneuron Pharmaceuticals Inc. (NASDAQ:IPIC) lost 38 centsto $8.63. The company said that it was issued on April 14 U.S.patent No. 5,014,880 covering Huperzine A analogs, potentialtreatments for Alzheimer's disease being developed inconjunction with the Mayo Foundation for Medical Educationand Research. Under an agreement with Mayo, Interneuron hascertain worldwide rights to patents covering the compound andits analogs, and to patents on improved, synthesized versions ofthe compound.

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