Second- and third-tier biotech share prices generally showedsmall to moderate gains on Friday, although the AMEXBiotechnology Index fell 4.95 points to 163.58. Many of thelarge-capitalization stocks in the index posted loses of morethan $1, led by Chiron Corp.'s $3 decline to $40.25. DeKalbGenetics Corp. jumped $2.25 to $32.25 and Alkermes Inc.added $1.75 to $15.

As measured by the index, biotech shares are down 18 percentin the last month and 36 percent since hitting a peak of 256.60on Jan. 14.

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