LifeCell Corp. on Tuesday said it has sold to RMC Inc. anexclusive worldwide sublicense to manufacture and sellLifeCell's tissue preservation technology in the electronmicroscopy market.

RMC of Tucson, Ariz., purchased the technology rights andexisting inventory, and will pay sales royalties to LifeCell ofThe Woodlands, Texas. Further details were not disclosed.

LifeCell's technology uses ultrarapid cooling and moleculardistillation drying of fresh tissue samples in preparation forelectron microscopy analysis. Molecular distillation involvesfreeze-drying at ultra-low temperatures, which prevents theformation of ice crystals that cause cells to rupture.

Other methods to prepare tissue samples include conventionalfreeze-drying and chemical preservation. Conventional freeze-drying can cause the formation of ice crystals, while chemicalpreservation precludes chemical analysis of samples, acompany spokesman said.

Other markets for the technology include transfusable redblood cell storage, mammalian cell cultures, porcine heartvalve tissue for human replacement, human saphenous veinsand biological wound dressing.

Privately held LifeCell licensed the process from theUniversity of Texas. The company was founded in 1986 as atechnology transfer from the university's Health ScienceCenter in Houston. -- KB

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