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BioWorld - Tuesday, February 17, 2026
Home » multiple system atrophy

Articles Tagged with ''multiple system atrophy''

Neurology/psychiatric

University of California divulges new α-synuclein, amyloid-β protein and MAPT propagation inhibitors

Oct. 1, 2025
The University of California has synthesized α-synuclein (SNCA) and/or amyloid-β protein and/or microtubule-associated protein tau (PHF-tau; MAPT) propagation inhibitors reported to be useful for diagnosis and treatment of multiple system atrophy, Parkinson’s disease and Alzheimer’s disease.
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Neurology illustration

Alterity develops novel MRI biomarker to track disease progression in MSA

Aug. 5, 2025
By Tamra Sami
No Comments
Alterity Therapeutics Ltd. helped develop a new neuroimaging biomarker called the multiple system atrophy index (MSA-AI), which looks to be a more reliable biomarker for tracking disease progression of MSA.
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Neurology illustration

Alterity develops novel MRI biomarker to track disease progression in MSA

July 31, 2025
By Tamra Sami
No Comments
Alterity Therapeutics Ltd. helped develop a new neuroimaging biomarker called the multiple system atrophy index (MSA-AI), which looks to be a more reliable biomarker for tracking disease progression of MSA. Developed using deep learning methods, the MSA-AI offers a superior, objective and quantifiable measure of brain atrophy in MSA patients.
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Central nervous system

Alterity’s ATH-434 looks to be disease modifying in multiple system atrophy

Feb. 4, 2025
By Tamra Sami
Alterity Therapeutics Ltd. reported positive top-line phase II results for lead candidate ATH-434 for treating multiple system atrophy, a rare neurological disorder similar to Parkinson's disease.
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Central nervous system

Alterity’s ATH-434 looks to be disease modifying in multiple system atrophy

Jan. 30, 2025
By Tamra Sami
Alterity Therapeutics Ltd. reported positive top-line phase II results for lead candidate ATH-434 for treating multiple system atrophy, a rare neurological disorder similar to Parkinson's disease.
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Neurology/psychiatric

New α-synuclein aggregation inhibitors disclosed in AC Immune patent

Dec. 12, 2024
AC Immune SA has divulged compounds acting as α-synuclein (SNCA) aggregation inhibitors reported to be useful for the treatment of multiple system atrophy (MSA), Parkinson’s dementia, Lewy body dementia, Alzheimer’s disease and Parkinson’s disease, among others.
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Cerebellum, brain stem, spinal cord

Alterity’s ATH-434 shows early response in multiple system atrophy

July 23, 2024
By Tamra Sami
Aussie biotech Alterity Therapeutics Ltd. released interim data of an open-label phase II trial for lead candidate ATH-434 for treating multiple system atrophy that showed 43% of participants improved, with 29% showing either stable or improved neurological symptoms.
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Cerebellum, brain stem, spinal cord

Alterity’s ATH-434 shows early response in multiple system atrophy

July 18, 2024
By Tamra Sami
Aussie biotech Alterity Therapeutics Ltd. released interim data of an open-label phase II trial for lead candidate ATH-434 for treating multiple system atrophy that showed 43% of participants improved, with 29% showing either stable or improved neurological symptoms.
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Cross section of brain
Neurology/Psychiatric

NLS Pharmaceutics licenses Aexon’s dual orexin receptor agonists

March 21, 2024
NLS Pharmaceutics Ltd. has entered into an exclusive worldwide license agreement with Aexon Labs Inc. granting NLS the opportunity to acquire global development and commercialization rights to Aexon’s next-generation nonsulfonamide dual orexin receptor agonists platform.
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Parkinson's disease illustration showing neurons containing alpha-synuclein
Diagnostics

[11C]MODAG-005 is tracer for synucleinopathies differential diagnosis

March 14, 2024
Aggregates of α-synuclein (αSyn) occur in multiple different neurodegenerative diseases.
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