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Home » Topics » Clinical

Clinical
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In the clinic for May 4, 2021

May 4, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Arch, Biolinerx, Checkmate, Cytokinetics, Cyxone, Genprex, HDT Bio, Ichnos, Immunitybio, Kiniksa, Merus, Obseva, Revolo, Rezolute, Tarsus, Vaxart, Verona.
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In the clinic for May 3, 2021

May 3, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Adverum, Aeglea, AGTC, Alnylam, Biogen, BMS, Eiger, Cabaletta, Denali, Jcyte, Lilly, Lineage, Mallinckrodt, Novan, Novartis, Novavax, Regulus, Repare, Sandoz, Sarepta, Seqirus, Sunovion, Xenothera, Zealand.
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In the clinic for April 30, 2021

April 30, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: AB, Eloxx, Mesoblast, Phathom, Scynexis, Synairgen, Tessa, Treadwell, Vifor.
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Preclinical through phase III, new COVID-19 therapy trials ramp up

April 30, 2021
By Michael Fitzhugh and Anette Breindl
Urgency to meet the world's worsening load of COVID-19 cases appeared unflagging Thursday, with four new trials kicking off to evaluate treatments aimed at keeping people from progressing to worsened disease and reports on two new variant-focused efforts yielding signs of preclinical promise.
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New COVID-19 therapy trials ramp up as weekly cases surpass previous peaks

April 29, 2021
By Michael Fitzhugh
Urgency to meet the world's worsening load of COVID-19 cases appeared unflagging Thursday, with four new trials kicking off to evaluate treatments aimed at keeping people from progressing to worsened disease and reports on two new variant-focused efforts yielding signs of preclinical promise.
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Person scratching arm

Cara jacking up efforts in pruritis, oral Korsuva drives on to phase III

April 29, 2021
By Randy Osborne
Despite stock-denting phase II data with the oral version of Korsuva (difelikefalin) for moderate to severe pruritis in patients with moderate to severe atopic dermatitis (AD), Cara Therapeutics Inc. CEO Derek Chalmers said the outcome “prioritizes moving forward. We got what we needed from the phase II trial,” which identified the patients most sensitive to the drug, nailed down a dose spectrum, and equipped the company to power a registrational effort, he said.
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In the clinic for April 29, 2021

April 29, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Abbvie, Adverum, Aerie, Akebia, Alphamab, Angion, Aptinyx, Atea, Brii, Can-Fite, Cara, Eisai, Galera, Hutchmed, Inflectis, Innovent, Partner, Quantum Leap, Pharnext, Reven, Takeda, Vascular, Vifor, Xencor, Zambon.
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Evolut device image

Medtronic reports promising early outcomes with Evolut TAVR system

April 28, 2021
By Meg Bryant
Medtronic plc reported positive interim results on the first 171 patients implanted with Evolut transaortic valve replacement (TAVR) devices in its OPTIMIZE PRO clinical trial. The postmarket, prospective, multicenter study is assessing procedural outcomes, including pacemaker rate, associated with in-procedure techniques and post-procedure TAVR care pathways when using the self-expanding, supra-annular Evolut Pro and Pro+ TAVR systems in patients with symptomatic severe aortic stenosis.
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Head to head: Beigene’s BTK inhibitor yields solid data against Imbruvica

April 28, 2021
By Lee Landenberger
Beigene Ltd.’s selective inhibitor, Brukinsa (zanubrutinib), made up for a 2019 miss in a head-to-head study against Johnson & Johnson and Abbvie Inc.’s Imbruvica (ibrutinib) with positive new data from a phase III trial in adults with relapsed or refractory chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma.
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In the clinic for April 28, 2021

April 28, 2021
Clinical updates, including trial initiations, enrollment status and data readouts and publications: Arrowhead, Beigene, Cadiol, Flexion, G1, Innovation, Lutris, Merck KGaA, Novaliq, Organicell, Redx, Resverlogix, Reveragen, Santhera, Takeda, Trillium.
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