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Home » Topics » Infection, BioWorld Science

Infection, BioWorld Science
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Infection

Pfizer discovers new nucleoprotein N inhibitors for RSV infection

June 30, 2025
Pfizer Inc. has described nucleoprotein N (respiratory syncytial virus [RSV]) inhibitors reported to be useful for the treatment of RSV infection.
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Infection

New PZA-mimicking prodrugs for tuberculosis disclosed in University of Maryland patent

June 30, 2025
University of Maryland has divulged pyrazinamide (PZA)-mimicking prodrugs reported to be useful for the treatment of tuberculosis.
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Infection

French scientists describe new treatment for cryptosporidiosis

June 30, 2025
Institut National Supérieur des Sciences Agronomiques de l’Alimentation et de l'Environnement has identified compounds reported to be useful for the treatment of cryptosporidiosis. 
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Infection

Shemyakin Institute of Bioorganic Chemistry divulges new antiviral photosensitizers for SARS-CoV-2

June 30, 2025
Shemyakin Institute of Bioorganic Chemistry has synthesized perylenylethynylphenol derivatives acting as photosensitizers for photodynamic therapy reported to be useful for the treatment of SARS-CoV-2 infection (COVID-19).
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3D illustration of leishmania parasite
Infection

Discovery and evaluation of new indole-dihydropyrimidinone derivatives for visceral leishmaniasis

June 27, 2025
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Visceral leishmaniasis is a fatal disease caused by the Leishmania parasite, affecting organs such as the liver and spleen. Visceral leishmaniasis is considered a neglected tropical disease and is estimated to cause between 50,000 and 90,000 cases and around 70,000 deaths per year.
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Infection

French researchers identify new agents for tuberculosis

June 26, 2025
Centre Hospitalier Regional Universitaire de Lille, Centre National de la Recherche Scientifique, INSERM, Institut Pasteur de Lille and the University of Lille have prepared and tested new tricyclic spirolactam compounds reported to be useful for the treatment of tuberculosis.
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Microscopic image of Group A streptococcus bacteria.
Immune

Evaxion unveils new vaccine program to prevent group A Streptococcus infections

June 26, 2025
No Comments
Evaxion A/S has added a new vaccine program, named EVX-B4, to its pipeline for prevention of group A Streptococcus (GAS) infections. Invasive GAS infections can cause diseases such as sepsis, toxic shock, rheumatic heart disease and necrotizing fasciitis.
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Infection

Scientiam Pharma reports new EBNA-1 inhibitors

June 25, 2025
Scientiam Pharma has disclosed new 6-aminophenanthridine derivatives acting as Epstein-Barr nuclear antigen 1 (EBNA-1) inhibitors reported to be useful for the treatment of Epstein-Barr virus (EBV)-associated disorders such as post-transplant lymphoproliferative disorder, multiple sclerosis and infectious mononucleosis.
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Infection

Italian researchers patent Flavivirus inhibitors

June 23, 2025
CNCCS SCARL Collezione Nazionale Dei Composti Chimici E Centro Screening and IRBM SpA have prepared new serine protease NS3/non-structural protein 2B (NS3/NS2B) (dengue virus) and/or (West Nile virus) and/or (Zika virus) and/or Japanese encephalitis virus inhibitors.
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Vaccine vials and syringe
Immune

CEPI-backed consortium to develop all-in-one filovirus vaccine

June 23, 2025
No Comments
A global consortium led by Adaptvac ApS aims to design and test a new vaccine that could offer broad protection against several filoviruses, including Zaire ebolavirus, Sudan ebolavirus and Marburg virus.
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