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BioWorld - Friday, September 22, 2023
Home » Topics » Newco news

Newco news
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Abraham Ceesay, CEO, Rapport
Newco news

Rapport launches with $100M series A plus J&J precision neuroscience platform

March 7, 2023
By Cormac Sheridan
No Comments
Rapport Therapeutics Inc. launched with $100 million in series A funding and ambitious plans to bring a hitherto unprecedented level of precision to therapies for neurological disease. Although the Boston-based company is new to the world, its underlying platform has been a decade in the making, and it already has one clinical-stage asset, which is in development for seizure disorders. It is currently undergoing a phase I trial.
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DNA NGS genome sequencing
Newco news

‘Biology no one else will have seen;’ startup Relation seeks new genetic targets

March 6, 2023
By Nuala Moran
No Comments
Newco Relation Therapeutics Ltd. is showing its colors after raising $25 million in a seed round to work on integrating single cell transcriptomics, functional genomics and machine learning – and cut through previously undecipherable combinatorial space – to find and validate drug targets in the non-coding genome.
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DNA in drug capsules
Newco news

New era in genetic medicines beckons as Aera arrives on scene

Feb. 28, 2023
By Caroline Richards
No Comments
Armed with $193 million in combined series A and B rounds, Aera Therapeutics aims to address current challenges with delivering gene-based therapies via a self-assembling human-derived protein platform it has in-licensed from a well-known Harvard scientist’s lab.
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Maximilien Levesque, co-founder and CEO, Aqemia
Newco news

Aqemia making waves in computational drug discovery

Feb. 27, 2023
By Cormac Sheridan
No Comments
For Aqemia SA, the year got off to a good start, as one of its pharma partners, Les Laboratoires Servier SAS, extended an existing collaboration to drug a supposedly undruggable immuno-oncology target, using its Launchpad artificial intelligence platform.
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Brain activity concept illustration
Newco news

Transcend raises $40M to develop methylone-based therapies

Feb. 24, 2023
By Lee Landenberger
No Comments
Transcend Therapeutics Inc. has closed on a series A funding of $40 million for its next-generation compound, methylone, an MDMA analogue, to be developed as a rapid-acting, disease-modifying, non-hallucinogenic treatment for neuropsychiatric conditions, including post-traumatic stress disorder.
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RNA
Newco news

Resalis closes $11M seed round to develop miR inhibitor for metabolic disease

Feb. 22, 2023
By Cormac Sheridan
No Comments
Resalis Therapeutics Srl closed a €10 million (US$10.6 million) seed round to progress toward the clinic a micro-RNA (miR) inhibitor in development for metabolic disease indications. Riccardo Panella, chief scientific officer and founder, identified the potential of a particular miR species, miR-22, as a target for metabolic syndrome while conducting studies on its potential role in oncology while at Harvard Medical School and Beth Israel Deaconess Medical Center.
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Liver and DNA
Newco news

Cargene’s siRNA therapy has potential to regenerate the liver and reverse fibrosis

Feb. 21, 2023
By Tamra Sami
No Comments
One of the most important transformations in the pharmaceutical industry over the next decade is the ability to modify genes or expression and go after any target, Cargene Biopharma Inc. CEO Kathy He told BioWorld, explaining that small molecules and large molecules can only go after 15% of the known targets. But the technology platform of short-interfering RNA (siRNA) opens a huge opportunity to make those inaccessible targets available, she said.
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Liver and DNA
Newco news

Cargene’s siRNA therapy has potential to regenerate the liver and reverse fibrosis

Feb. 17, 2023
By Tamra Sami
No Comments
One of the most important transformations in the pharmaceutical industry over the next decade is the ability to modify genes or expression and go after any target, Cargene Biopharma Inc. CEO Kathy He told BioWorld, explaining that small molecules and large molecules can only go after 15% of the known targets. But the technology platform of short-interfering RNA (siRNA) opens a huge opportunity to make those inaccessible targets available, she said.
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Brain and neural networks
Newco news

Newly public Coya takes on neurodegenerative disease with Tregs

Feb. 15, 2023
By Jennifer Boggs
No Comments
Fresh off an end-of-year IPO, Coya Therapeutics Inc. is gearing up for clinical testing with its lead Treg-enhancing biologic in neurodegenerative disease, aiming to build on a wealth of academic-generated data highlighting the potential of Treg therapy to attack the neuroinflammation underlying diseases such as amyotrophic lateral sclerosis and Alzheimer’s disease.
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Older person holding cane
Newco news

Cambrian’s Isterian sees aging in fibrosis as more than skin deep

Feb. 14, 2023
By Anette Breindl
No Comments
Compared to the issues that come with, say, a failing liver, skin aging can look like more of a vanity problem. But aging in both tissues, and multiple others, is driven by the same underlying molecular mechanisms. One of those mechanisms is fibrosis, the cross-linking of extracellular matrix (ECM) proteins that leads to tissue stiffening. Anti-aging company Cambrian Biopharma Inc. has argued that stiffening of the ECM should be considered one of the formal hallmarks of aging.
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