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Newco news

Circode applies circRNA to heart disease drug R&D, in vivo CAR T

July 11, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Circode Biomed Co. Ltd. is set to begin clinical trials of HM-2002, a circular RNA (circRNA)-based drug for ischemic heart disease, having gained IND clearance in China Jan. 10 and the U.S. on May 30, Circode CEO Chenxiang Tang recently told BioWorld.
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Cancer

Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 11, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
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Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 10, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
Read More

Actithera raises $75M series A for FAP-targeted radiopharmaceuticals

July 9, 2025
By Nuala Moran
No Comments
Actithera A/S is poised to bring small-molecule pharmacokinetics to radiopharmaceuticals after closing a $75.5 million series A that will fund initial clinical development of a candidate targeting the elusive fibroblast activation protein (FAP).
Read More

Veritas, Mitsubishi Gas Chemical partner for new ASO candidates

July 8, 2025
By Marian (YoonJee) Chu
No Comments
Veritas In Silico Inc. (VIS) entered a joint research agreement with Mitsubishi Gas Chemical Co. Inc. to use VIS’s mRNA structural motif analyzing platform technology, called Ibvis, to develop antisense oligonucleotide drug candidates.
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Hand holding money plant
Endocrine/metabolic

Abvance Therapeutics secures seed funding to limit glucose lows

June 30, 2025
By Brian Orelli
No Comments
Abvance Therapeutics Inc. secured an undisclosed amount of capital in a seed round led by Zubi Capital to support development of an insulin and glucagon combination product that the company has been in the process of developing for approximately 18 months. “We’re very excited that this round is able to get us positioned for a successful series A once we meet some internal confidential milestones,” Edward Raskin, CEO of Abvance, told BioWorld.
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Hand holding money plant
Newco news

Abvance Therapeutics secures seed funding to limit glucose lows

June 26, 2025
By Brian Orelli
No Comments
Abvance Therapeutics Inc. secured an undisclosed amount of capital in a seed round led by Zubi Capital to support development of an insulin and glucagon combination product that the company has been in the process of developing for approximately 18 months.
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Drug Farm harvests new immunomodulators with AI-gene editing tech

June 24, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Yao Yuan Biotechnology Ltd., also known as Drug Farm, is advancing a portfolio of immune-modulating therapies for various indications including hepatitis B virus, hepatocellular cancer and a relatively new rare genetic disease called ROSAH, an acronym for retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache.
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AI-generated illustration of DNA double helix

Drug Farm harvests new immunomodulators with AI-gene editing tech

June 20, 2025
By Marian (YoonJee) Chu
No Comments
Shanghai Yao Yuan Biotechnology Ltd., also known as Drug Farm, is advancing a portfolio of immune-modulating therapies for various indications including hepatitis B virus, hepatocellular cancer and a relatively new rare genetic disease called ROSAH, an acronym for retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis, and headache.
Read More
3D illustration of a chain of amino acid or biomolecules called protein
Drug design, drug delivery & technologies

Alphadesign: AI creating proteins from scratch

June 19, 2025
By Nuala Moran
No Comments
The Alphafold machine learning system for predicting a protein’s structure from its amino acid sequence has been adapted to make it possible to design de novo proteins that fold in a particular way and bind to prespecified target proteins. The sister system, called Alphadesign, works by generating random strings of amino acids, using Alphafold to predict their structure, and then iteratively optimizing the design.
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