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Home » Topics » Asia-Pacific » Japan

Japan
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Brain with handshake and cityscape

New schizophrenia target draws Boehringer in €755M Sosei deal

March 11, 2024
By Jennifer Boggs
Sosei Group Corp. is getting €25 million (US$27.3 million) up front in a global collaboration and option-to-license deal with Boehringer Ingelheim GmbH aimed at developing GPR52 agonists, a new target for schizophrenia designed to potentially address positive, negative and cognitive symptoms at the same time.
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Hands holding tablet and glass of water

Shionogi’s oral COVID-19 antiviral wins full approval in Japan

March 6, 2024
By Marian (YoonJee) Chu
Shionogi & Co. Ltd., of Osaka, Japan, gained standard approval from Japan’s Ministry of Health, Labour and Welfare for Xocova (ensitrelvir fumaric acid) on March 5, making it the first COVID-19 antiviral to win full approval in the country.
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Takeda, Biological E. partner to widen global access to Qdenga

March 5, 2024
By Tamra Sami
In a move to widen global access to its Qdenga dengue vaccine, Takeda Pharmaceutical Co. Ltd. is partnering with India’s Biological E. Ltd. to manufacture Qdenga (TAK-003).
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EMA validates two filings for Daiichi-Astrazeneca’s ADC

March 5, 2024
By Marian (YoonJee) Chu
The EMA validated two marketing approval applications of Daiichi Sankyo Co. Ltd. and Astrazeneca plc’s antibody-drug conjugate (ADC) datopotamab deruxtecan (dato-dxd) on Mar. 4, for two types of lung and breast cancer.
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EMA validates two filings for Daiichi-Astrazeneca’s ADC

March 4, 2024
By Marian (YoonJee) Chu
The EMA validated two marketing approval applications of Daiichi Sankyo Co. Ltd. and Astrazeneca plc’s antibody-drug conjugate (ADC) datopotamab deruxtecan (dato-dxd) on Mar. 4, for two types of lung and breast cancer.
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Boston Scientific Corporation AGENT Drug Coated Balloon

FDA approves ‘needle-moving’ Boston Scientific’s Agent balloon

March 1, 2024
By Annette Boyle
On March 1, Boston Scientific Corp.’s Agent drug-coated balloon (DCB) became the first DCB to gain U.S. FDA approval for treatment of in-stent restenosis in patients with coronary artery disease. With more than 100,000 patients already treated in Europe, Latin America and Japan, it’s no secret Agent provides significant benefit compared to balloon angioplasty or drug-eluting stents (DES) for the approximately 10% of patients with coronary stents who experience subsequent narrowing of the treated vessel.
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Takeda, Biological E. partner to widen global access to Qdenga

Feb. 28, 2024
By Tamra Sami
In a move to widen global access to its Qdenga dengue vaccine, Takeda Pharmaceutical Co. Ltd. is partnering with India’s Biological E. Ltd. to manufacture Qdenga (TAK-003).
Read More
CAR T cells attacking cancer cell

Astellas’ Xyphos teams with Kelonia on cancer drugs in $800M deal

Feb. 20, 2024
By Marian (YoonJee) Chu
San Francisco-based Xyphos Biosciences Inc. is pooling technology platforms with Boston’s Kelonia Therapeutics Inc. in a novel immuno-oncology (I-O) drug discovery deal that could fetch more than $800 million. Xyphos and Kelonia will collaborate to develop a maximum of two in vivo CAR T-cell therapy programs, utilizing both Kelonia’s in vivo gene placement system called iGPS and Xyphos’ Accel technology platform.
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Hands holding gears

Ono inks deals with Shattuck, Numab in autoimmune disease, oncology

Feb. 20, 2024
By Tamra Sami
Ono Pharmaceutical Co. Ltd. inked deals with Shattuck Labs Inc. and Numab Therapeutics AG aimed at bolstering its pipeline in oncology and autoimmune and inflammatory diseases. Ono struck a drug discovery collaboration and option agreement with Shattuck Labs to generate bifunctional fusion proteins for pathways involved in autoimmune and inflammatory diseases. It also signed a global research, development and commercialization deal with Numab for its NM-49, a multispecific antibody designed to activate tumor-associated macrophage phagocytosis for treating cancers.
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3D dollar sign

Kyowa pays $100M up front for Bridgebio’s infigratinib in Japan

Feb. 20, 2024
By Marian (YoonJee) Chu
Palo Alto, Calif.-based Bridgebio Pharma Inc. will hand over development and sales of its rare bone growth disorder therapy, infigratinib, in Japan to Kyowa Kirin Co. Ltd. under its latest exclusive licensing deal.
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