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Musculoskeletal

Alebund Pharmaceuticals discovers new complement factor B inhibitors

Dec. 2, 2025
Alebund Pharmaceuticals (Hong Kong) Ltd. has described complement factor B (CFB) inhibitors reported to be useful for the treatment of glomerular disorders and rheumatoid arthritis.
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Cancer

New CDK inhibitors disclosed in Adlai Nortye patent

Dec. 2, 2025
Adlai Nortye Biopharma Co. Ltd. and Adlai Nortye Pte Ltd. have divulged cyclin-dependent kinase 2 (CDK2) and/or CDK4 and/or CDK6 inhibitors reported to be useful for the treatment of inflammatory disorders, immunological disorders and cancer.
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Cancer

Chengdu Chipscreen Pharmaceutical describes new WRN inhibitors

Dec. 2, 2025
Chengdu Chipscreen Pharmaceutical Ltd. has identified Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of cancer.
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Cancer

Abbisko Therapeutics divulges new SMARCA2 inhibitors

Dec. 2, 2025
Abbisko Therapeutics Co. Ltd. has synthesized probable global transcription activator SNF2L2 (SMARCA2; BAF190B; SNF2-α) inhibitors reported to be useful for the treatment of cancer.
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Endocrine/metabolic

Chinese researchers patent new URAT1 inhibitors

Dec. 2, 2025
Apichope Pharmaceutical Co. Ltd., Guangzhou Lianrui Pharmaceutical Co. Ltd. and Guangzhou Runlin Pharmaceutical Technology Co. Ltd. have disclosed solute carrier family 22 member 12 (SLC22A12; URAT1) inhibitors reported to be useful for the treatment of hyperuricemia, nephropathy and gout.
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Cancer

Chia Tai Tianqing Pharmaceutical discovers new WRN inhibitors

Dec. 1, 2025
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has described Werner syndrome ATP-dependent helicase (WRN; RECQ3; RECQL2) inhibitors reported to be useful for the treatment of colorectal cancer.
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Endocrine/metabolic

TSHR antagonists disclosed in Genescience patent

Dec. 1, 2025
Genescience Pharmaceuticals Co. Ltd. has divulged thyroid-stimulating hormone (thyrotropin) receptor (TSHR) antagonists reported to be useful for the treatment of hyperthyroidism, Grave’s disease and thyroid-associated ophthalmopathy (Grave’s ophthalmopathy).
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Endocrine/metabolic

Di’ao Group Chengdu Pharmaceutical describes new GLP-1R agonists

Dec. 1, 2025
Di’ao Group Chengdu Pharmaceutical Co. Ltd. has identified glucagon-like peptide 1 receptor (GLP-1R) agonists reported to be useful for the treatment of diabetes, dementia, obesity, metabolic syndrome, metabolic dysfunction-associated steatotic liver disease (MASLD), dyslipidemia, stroke and cardiovascular disorders, among others.
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Diagnostics

US researchers divulge new PET and SPECT imaging agents

Dec. 1, 2025
Cornell University and The General Hospital Corp. (Massachusetts General Hospital) have synthesized conjugates comprising a targeting moiety covalently linked to a radiolabeled metal chelator through a linker acting as positron emission tomography (PET) or single-photon emission computerized tomography (SPECT) imaging agents reported to be useful for diagnosis and treatment of cancer.
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Neurology/psychiatric

Shenzhen Icarbonx Intelligent Peptide Pharmaceutical patents new peptides targeting BRAG2

Dec. 1, 2025
Shenzhen Icarbonx Intelligent Peptide Pharmaceutical Technology Co. Ltd. has disclosed peptides targeting IQ motif and SEC7 domain-containing protein 1 (IQSEC1; BRAG2) reported to be useful for the treatment of stroke, major depression, substance abuse and dependence, and Alzheimer’s disease.
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