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Home » Newsletters » BioWorld

BioWorld

Feb. 8, 2018

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Earnings

Seattle Genetics Inc., of Bothell, Wash., reported that sales of its lymphoma therapy, Adcetris (brentuximab vedotin), hit $83.7 million in the fourth quarter, up 18 percent from net sales of $70.8 million in the fourth quarter of 2016. Read More

In the clinic

Akcea Therapeutics Inc., of Cambridge, Mass., said it completed enrollment in a phase IIb study of AKCEA-APO(a)-LRx in patients with high Lp(a) and established cardiovascular disease to determine the dose level and frequency of administration for a planned phase III cardiovascular outcome study and to determine the safety and tolerability profile of the antisense drug. Read More

Other news to note

V Clinbio Inc., of Princeton, N.J., acquired a 49.98 percent equity stake in its partner, Cellix Bio Private Ltd., of Hyderabad, India. Read More

Financings

Viking Therapeutics Inc., of San Diego, announced the closing of its underwritten public offering of about 12.7 million shares of common stock for gross proceeds of about $63.3 million, with underwriters exercising their full option to buy additional shares. Read More

Chinese, U.S. universities join forces in research, translational medicine

HONG KONG – As a part of China's development plan for the Guangdong-Hong Kong-Macau Greater Bay Area, the Hong Kong Polytechnic University (PolyU) and its allies from the city cluster have established collaborations with U.S. institutions in the field of biotech research and translational medicine. Read More

Asparagine promotes breast cancer metastases by way of EMT

LONDON – New research has pinpointed asparagine as a key factor in promoting the formation of metastases in breast cancer and suggests a probable mechanism for how the bioavailability of a single amino acid enables tumor cells to colonize secondary sites. Read More

Biosimilar competition brings little relief to pain of RA drug prices

Nearly 35 years after Hatch-Waxman cleared the way for a robust generics industry, the U.S. is still waiting for lightning to strike twice, this time with biosimilars. Read More

Tysabri's stroke strikeout turns eyes to phase III bid, 'leading' AD pipeline hope

Having taken in the data from the phase IIa Action study with Tysabri (natalizumab) by Biogen Inc., investors weren't too surprised by results from the phase IIb, dose-ranging Action 2 experiment in acute ischemic stroke (AIS) that turned up no improvement compared to placebo. Read More

Gilead losing ground in HCV sales, sees HIV win ahead

Gilead Sciences Inc. reported that fourth-quarter sales of its hepatitis C virus (HCV) therapies halved since last year, falling to $1.5 billion from $3.2 billion in the fourth quarter of 2016 as new competition arrived on the scene and fewer patients started treatment. Read More

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