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BioWorld - Monday, March 23, 2026
Home » Newsletters » BioWorld

BioWorld

March 28, 2018

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Financings

Sorrento Therapeutics Inc., of San Diego, is selling $120.5 million of unsecured convertible notes in a private placement to accredited investors.  Read More

Other news to note

Cyxone AB, of Stockholm, concluded the first phase of a pilot study investigating the effect of cyclotides against inflammatory bowel disease (IBD) in an acute animal model of the condition.  Read More

Australia opens provisional approval path, SAS to speed patient access to new drugs

PERTH, Australia – Pharmaceutical companies wanting to submit new drug applications in Australia now have additional pathways thanks to new drug legislation aimed at speeding access to therapies. Read More

Year-old Caelum sharpens its 'chisel' against AL amyloidosis

Caelum Biosciences Inc. enhanced its cachet with an analysis of data from the phase Ib trial of its chimeric fibril-reactive monoclonal antibody (MAb), CAEL-101 (11-1F4), that showed a correlation between sustained decrease in N-terminal pro-brain natriuretic peptide (NT-proBNP) levels and improvement in global longitudinal strain (GLS) in individuals with cardiac amyloid light chain (AL) amyloidosis. Read More

New approaches could broaden antibiotic space

As antibody developers can attest, many antibodies can bind to cells. But most of them don't do anything of therapeutic value after they do. Read More

Kineta crafting seaworthy RIG in cancer after Merck sets sail with German buy

Last year, after Merck & Co. Inc. "put this stake in the ground" to establish the importance of the retinoic acid-induced gene I (RIG-I) pathway by acquiring Rigontec GmbH, other pharma firms sat up and took notice, said Kristin Bedard, chief scientific officer of Kineta Inc. Read More

PDAC gives qualified support to Lucemyra to help with opioid withdrawal

U.S. Worldmeds LLC's Lucemyra (lofexidine) moved another step closer to the U.S. market Tuesday with an 11-1 advisory committee vote recommending FDA approval of the drug to mitigate symptoms of opioid withdrawal. Read More

Regulatory actions for March 27, 2018

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Clinical data for March 27, 2018

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