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Home » Newsletters » BioWorld

BioWorld

Nov. 26, 2019

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Treble in mind: Chemocentryx’s successful phase III vaults shares nearly threefold

Positive phase III data from the Advocate trial by Chemocentryx Inc. and Vifor Fresenius Medical Care Renal Pharma caused Chemocentryx’s stock (NASDAQ:CCXI) to dramatically rise 281% on Tuesday, clearing the way to an NDA filing for the star small-molecule attraction, avacopan, an oral, selective complement 5a receptor inhibitor. Read More

‘Tacrolimust’ hold bright future, Asahi price: $1.3B for Veloxis with Envarsus kidney transplant formulation

Veloxis Pharmaceuticals A/S’ board chairman, Michael Heffernan, said investors will find out in “the next four weeks” more details related to the $1.3 billion takeover by Tokyo-based Asahi Kasei Corp., which gets control of Envarsus XR, an improved formulation of tacrolimus for prophylaxis of organ rejection in kidney transplant patients converted from tacrolimus and for use in de novo kidney transplant patients. Read More
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Australia’s Kazia Therapeutics reports positive interim results in phase II glioblastoma trial

PERTH, Australia – Sydney-based Kazia Therapeutics Ltd.’s shares soared nearly 82% this week on positive interim results for lead molecule GDC-0084 in a phase II glioblastoma trial. Read More

World's biggest hematology confab to feature new therapies, big-picture research

With nearly 5,000 abstracts on tap for this December's American Society of Hematology (ASH) meeting in Orlando, Fla., organizers of the annual conference have highlighted a multitude of new advances in the event's programming. Read More
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Targetable dopamine receptor influences childhood-onset asthma

Children are more susceptible to developing allergic asthma than adults. An estimated 6 million children have allergic asthma, making asthma one of the most common long-term diseases of childhood. Asthma is potentially life-threatening, yet there is no cure, rather only management of symptoms. Progress in understanding the disease was reported in the Dec 17, 2019, issue of Immunity. Read More

GBT’s Oxbryta gains nod in SCD; one-two punch for patients with Novartis win

Less than two weeks after giving the go-ahead to Novartis AG for Adakveo (crizanlizumab) to reduce the frequency of vaso-occlusive crises (VOCs) in adult and pediatric patients ages 16 and older with sickle cell disease (SCD), the FDA cleared – well ahead of its Feb. 26, 2020, PDUFA date – Oxbryta (voxelotor), from Global Blood Therapeutics Inc. (GBT), for SCD in adults and pediatric patients ages 12 and up. 

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Financings for Nov. 26, 2019

Biopharmas raising money in public or private financings. Read More

In the clinic for Nov. 26, 2019

Clinical updates, including trial initiations, enrollment status and data readouts and publications. Read More

Other news to note for Nov. 26, 2019

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief. Read More

Regulatory actions for Nov. 26, 2019

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations. Read More

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