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Home » Newsletters » BioWorld

BioWorld

Feb. 20, 2020

View Archived Issues
Cancer-gene-therapy-T-cell

Immatics gets $50M up front in engineered T-cell therapy deal with GSK

DUBLIN – Immatics Biotechnologies GmbH is banking $50 million up front and could earn up to $550 million more in per-product milestones from an adoptive cell therapy deal in solid tumor indications with Glaxosmithkline plc, which initially involves two autologous cell therapies engineered to express T-cell receptors (TCRs) that bind novel cancer targets. Immatics would receive royalties on sales of any approved therapies. Read More

VMAT2 carry-through brings Waterloo for Austedo TS bid by Teva

Teva Pharmaceutical Industries Ltd.’s Austedo (deutetrabenazine) lived up to the lack of expectations in pediatric Tourette syndrome (TS), missing identical primary endpoints in a pair of late-stage trials. Read More
Biosimilars

FDA prepares for NDA-to-BLA deeming day

With deeming day a little more than a month away, the FDA is taking final steps to ease the transition of simple proteins approved as new drug applications (NDAs) to biologic license applications (BLAs). The March 23 change will open drugs such as insulin and various hormones to new competition, likely bringing in the next wave of biosimilars. And this time, interchangeability could be riding the crest. Read More
DNA-sequencing.png

Passengers, noncoding genome affect how cancers play out

Beyond every binary is a more complex reality. And so it is with driver and passenger mutations. The separation of tumor mutations into drivers and passengers underpins much progress in the development of targeted therapies. By looking at passenger mutations more carefully, though, researchers at Yale University have shown that passenger mutations, too, played a role in how tumors progressed. Read More
India-pill-bottle-drugs

India ramps up efforts to move up biotech value chain

HYDERABAD, India – Multinationals and domestic companies are stepping up research in India, including working to leverage the country’s digital and entrepreneurial capabilities, to boost India’s capabilities and market share in more innovative biologic drugs. Read More

Tackling infectious diseases, Appili closes $7.7M public offering and pursues collaborations

Infectious disease has been rough going for all comers the past few years, as companies have floundered. Appili Therapeutics Inc.’s CEO, Armand Balboni saw the troubles others encountered with the indication and also saw companies with thin pipelines struggle, but it hasn’t stopped him from forging on. Read More

Zelira’s medicinal cannabis therapy meets primary endpoints in phase I/II insomnia trial

PERTH, Australia – Medicinal cannabis company Zelira Therapeutics Ltd. reported that its ZLT-101 therapy met the primary endpoint of a statistically significant improvement in insomnia in a phase Ib/IIa study in patients diagnosed with chronic insomnia. Read More
Cancer-cells-pic.png

Nantomics’ deep learning algorithm provides fast identification of cancer marker

Nantomics LLC, of Culver City, Calif., reported that research based on the company’s deep learning system has been published in a peer-reviewed journal, highlighting the algorithm’s ability to discern which mutation drives a patient’s breast cancer. Read More

Appointments and advancements for Feb. 20, 2020

New hires and promotions in the biopharma industry, including: Askbio, Galectin, Kane, Vivera. Read More

Financings for Feb. 20, 2020

Biopharmas raising money in public or private financings, including: Aeterna Zentaris, Alladapt, Axovant, Bioxcel, Deciphera, Hemostemix, Spruce. Read More

In the clinic for Feb. 20, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Advaxis, Agenus, Axsome, Breath, Brickell, Compugen, Cyclo, Dyve, Galderma, Index, Magenta, Moleculin, Polyphor, Teva, Vascular Biogenics, Vistagen, Zambon. Read More

Other news to note for Feb. 20, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Bonus Biogroup, Cytokinetics, Dermira, Forte, Fresenius, FSD, Hemogenyx, Hepion, Hummingbird, Lantheus, Lilly, Mesoblast, Molecular Templates, Mycenax, Novan, Progenics, Recordati, Restorbio, Stonewise, Tocagen, Vifor, Wize, Xbiotech. Read More

Regulatory actions for Feb. 20, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Adial, Forma, Heron . Read More

Regulatory front for Feb. 20, 2020

The latest global regulatory news, changes and updates affecting biopharma, including: Vertex Pharmaceuticals. Read More

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