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Home » Newsletters » BioWorld

BioWorld

July 14, 2020

View Archived Issues
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The ‘RET’ price? Blueprint banking $775M on pralsetinib Roche co-commercialization deal

DUBLIN – Blueprint Medicines Corp. is banking $775 million, including $675 million up front and another $100 million as an equity investment, from a co-commercialization deal with Roche Holding AG and its Genentech subsidiary involving RET inhibitor pralsetinib. The deal also includes up to $927 million in development, regulatory and commercial milestones, $90 million of which are described as “near-term,” plus tiered royalties on ex-U.S. sales, ranging from the high-teens to mid-twenties. Read More
China U.S. deal

Junshi taps Revitope in discovery stage to develop antibody-based cancer immunotherapies

BEIJING – Besides advancing its neutralizing antibodies for COVID-19, Shanghai Junshi Biosciences Co. Ltd. is aiming to expand its pipeline. On July 13, it entered a collaboration with Revitope Oncology Inc. Read More
Tumor necrosis factor (TNF), a cytokine involved in inflammation processes

AD not in-‘soluble’ after all? Street likes Inmune’s bet on next-gen TNF

Inmune Bio Inc. CEO Raymond Tesi told BioWorld his firm is taking an “oncology-style” approach to Alzheimer’s disease (AD) as the firm tests next-generation tumor necrosis factor (TNF) inhibitor XPro-1595 against neuroinflammation. Read More
R&D spending

Beigene makes history with $2B direct offering to fund R&D

HONG KONG – Chinese biotech giant Beigene Ltd. launched a $2.08 billion registered direct offering this week, the largest offering of its kind ever recorded globally. Beigene executives said net proceeds will primarily be used for general corporate purposes such as R&D for existing or new drugs in the pipeline. Read More
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Tackling COVID-19 provides reminder about the need for new anti-infectives

While biopharmaceutical research is currently concentrating on the threat posed by the COVID-19 pandemic, the disease has provided a sharp reminder that our focus should not be lost on infectious diseases as a whole, along with the growing global problem of antibiotic resistance (AMR), which has the potential to dwarf COVID-19 in terms of deaths and economic costs, according to the International Federation of Pharmaceutical Manufacturers and Associations (IFPMA). Read More

Cytokinetics inks collaboration and royalty deal with RTW and Ji Xing

Cytokinetics Inc.’s new deal with RTW Investments gives the company a new presence in Asia and a strong influx of cash that should last at least two or three years. Read More

Give myeloma patients the choice, ODAC tells FDA

Patients with triple-refractory multiple myeloma who are running out of options may soon have a new lifeline. That’s if the FDA follows the unanimous vote of its Oncologic Drugs Advisory Committee (ODAC) and grants accelerated approval to Glaxosmithkline plc’s (GSK) belantamab mafodotin as a fifth-line therapy for adults with relapsed or refractory multiple myeloma. Read More
Coronavirus vaccine, therapeutic illustration

China’s Kintor to provide AR antagonist for COVID-19 trial in Brazil

BEIJING – Androgen receptor (AR) antagonist developer Kintor Pharmaceutical Ltd., of Suzhou, China, is going to provide its proxalutamide (GT-0918) to an ongoing clinical trial in male patients, led by U.S. firm Applied Biology Inc., in Brazil for COVID-19, after preliminary clinical research suggested a potential link between androgenetic alopecia and COVID-19 pathogenesis. Read More
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Review in U.K. finds that patient concerns have been ignored for decades with harmful consequences

LONDON – An independent U.K. inquiry has found that failure to take seriously concerns raised by patients has resulted in life-threatening problems caused by medical devices and drugs being ignored for decades. Read More

Verrica gets expected CRL for molluscum contagiosum drug

Two weeks after receiving a letter from the FDA citing deficiencies in the NDA seeking approval for VP-102 (cantharidin 0.7% topical solution) in molluscum contagiosum, Verrica Pharmaceuticals Inc. disclosed an unsurprising complete response letter. Read More

Appointments and advancements for July 14, 2020

New hires and promotions in the biopharma industry, including: Allovir, Calithera, Predictive Oncology, Recce, Scholar Rock, Vor. Read More

Earnings for July 14, 2020

Quarterly snapshots from biopharma companies with marketed products, including: Flexion. Read More

Financings for July 14, 2020

Biopharmas raising money in public or private financings, including: Aldeyra, Altimmune, Arctic Vision, Ionctura, Macomics, Osmotica, Revolution, Santhera. Read More

In the clinic for July 14, 2020

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Akebia, Albireo, Bioarctic, Biogen, Dynavax, Eisai, Galera, GSK, Histogen, Inmune, Landos, Medicago, NMD, Rigel, Sotio. Read More

Other news to note for July 14, 2020

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Acepodia, Arch Biopartners, Arcus, Astrazeneca, Avita, BMS, Caris, Cellink, Daiichi, Domainex, Educell, Emergent, Fate, Gilead, Immunomedics, Invivoscribe, Iqvia, JW Therapeutics, Kugelmeiers, Lamassu, Merus, Orgenesis, Pascal, PDS, Roche, Sanofi, Vitro, Xbiotech. Read More

Regulatory actions for July 14, 2020

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Celyad, Deciphera, Fosun, IMV, Inflazome, Janssen, Vanda, Verrica. Read More

Regulatory front for July 14, 2020

The latest global regulatory news, changes and updates affecting biopharma, including: Newlink. Read More

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