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Home » Newsletters » BioWorld

BioWorld

May 19, 2021

View Archived Issues
Pill in immersive interface

Exscientia and BMS expand AI drug discovery deal, with potential $1.2B+ value

Building on a deal first struck in 2019, artificial intelligence (AI) specialist Exscientia Ltd. has agreed to take responsibility for a multitarget drug discovery collaboration with Bristol Myers Squibb Co. that could be worth more than $1.2 billion in all. The expanded collaboration, first established with BMS-acquired Celgene Corp., includes $50 million in up-front funding, up to $125 million in near to mid-term potential milestones, plus additional clinical, regulatory and commercial payments. It remains focused on small-molecule drug candidates in areas including oncology and immunology. Read More

Reata skips the type C and heads for a pre-NDA in FA

There’s been a change of plans. Following a preliminary review of briefing materials for a type C meeting, the FDA told Reata Pharmaceuticals Inc. that a pre-NDA meeting is instead the next best step in the development of omaveloxolone (RT-408) for treating Friedreich’s ataxia (FA). Read More
Pink and orange test tubes

COVID-19 R&D drives sector’s research spending in Q1

The top 100 public biopharmaceutical companies with market caps greater than $1 billion, and excluding big pharma companies, spent a total of almost $12 billion on R&D in the first quarter of 2021, compared to $9.4 billion invested last year. Read More

Don’t walk away, Reneo poised to take flight in PPAR delta; Astellas too?

Reneo Pharmaceuticals Inc.’s $93.8 million IPO last month brought renewed attention to primary mitochondrial myopathy (PMM), a genetic disorder that impairs oxidative phosphorylation, affecting mainly muscles. The San Diego-based firm sold about 6.2 million shares at $15 each, but the stock (NASDAQ:RPHM) has since taken a dive, closing May 19 at $8.83. Read More
Nonprofit stamp

Pandemic efforts dominate with 76% of the nonprofit deal and grant value

Although more than a third of U.S. citizens are fully vaccinated from COVID-19 and society moves closer to normalcy in many parts of the world, the SARS-CoV-2 virus continues to dramatically impact biopharma dealmaking with nonprofit entities, as well as grant awards. Read More

Antengene, Calithera reach deal for CD73 inhibitor

BEIJING, China and SANTANDER, Spain – Antengene Corp. and Calithera Biosciences Inc. entered a worldwide exclusive license agreement to develop and market the CD73 inhibitor CB-708 (ATG-037), as part of a push to use the small-molecule inhibitor to grab significant market share in Asia Pacific and global markets. Read More

FDA’s crowdsourcing challenge targets use of pooled analyses in cancer studies

The FDA’s Oncology Center of Excellence is hoping to hear from stakeholders on how data from pooled clinical analyses can be put to further use. Read More

Appointments and advancements for May 19, 2021

New hires and promotions in the biopharma industry, including: Acacia, Appia, Aravive, ARS, Artiva, Campbell, Clene, Fore, Gensight, Landos, Logicbio, Promis, Qualigen, Redx, Senti, Shoreline, Tevard, Viewpoint Molecular Targeting. Read More

Financings for May 19, 2021

Biopharmas raising money in public or private financings, including: Allarity, Eloxx, Hibercell, Isofol, Maia, Thinkcyte. Read More

In the clinic for May 19, 2021

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Acceleron, Apeiron, Astrazeneca, Biomarin, CNS, Cytokinetics, Galapagos, Idera, Immunocore, Pfizer, Silence, Veru. Read More

Other news to note for May 19, 2021

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Accerise, Acepodia, Achilles, Amerimmune, Atyr, Autolomous, Avidity, Basilea, Bioray, Cytoreason, Dr. Reddy's, Ethypharm, Ferring, Histogen, Moderna, Nascent, Organicell, Pfizer, Postera, Quercis, Replicel, Sapience, Sosei, Synaptogenix, Teneobio. Read More

Regulatory actions for May 19, 2021

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Beigene, Bioxcel, Genetx, Iovance, Myovant, Polypid, Reata, Ultragenyx. Read More

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