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Home » Newsletters » BioWorld

BioWorld

March 3, 2023

View Archived Issues
Woman steadying hand tremor

Praxis theory not foiled but stock shaken by tremor phase IIb; revising TETRAS play for next study

Praxis Precision Medicines Inc. CEO Marcio Souza said it would be “disingenuous not to move forward” – U.S. FDA willing – into a phase III effort with an alternate design targeted for the second half of this year, given top-line results from the phase IIb Essential-1 study with ulixacaltamide (PRAX-944) for essential tremor. Read More

Revolution mitigates future milestone losses with $300M stock offer

Targeted oncology firm Revolution Medicines Inc. is seeking $300 million through a public offering as it prepares to say farewell to Sanofi SA, partner for its most advanced RAS program, and with it the prospect of earning more than $500 million in developmental and regulatory milestone payments and tiered royalties on annual net sales. Read More
Epidermal growth factor receptor (EGFR)

Abbisko out-licenses preclinical EGFR candidate to Allist for $188M

Abbisko Therapeutics Co. Ltd. and Allist Pharmaceuticals Co. Ltd. signed an exclusive licensing deal that gives Allist rights to develop, manufacture and commercialize Abbisko’s ABK-3376, an EGFR tyrosine kinase inhibitor for $188 million plus royalties. Read More

Immorna nets $100M in two financing rounds to develop RNA therapies

Immorna Biotechnology Co. Ltd. raised nearly $100 million in series A+ and A++ financing rounds to speed up the clinical development and commercialization of its RNA-based therapeutics. Founded in 2019, Immorna develops therapeutics and vaccines based on its RNA platforms, including conventional, self-replicating and circular RNA. Read More
Biocom pic 1 3-3

Biocom 2023: Venture capitalists spill the beans

According to venture capitalists on three different panels at Biocom California’s Global Life Science Partnering & Investor Conference, there’s still money available for newcos looking to get started. But the pitch they’re going to have to make to VCs is a little different than what would have worked a few years ago. Read More

As Lilly caps insulin prices, Sanders nudges Sanofi and Novo Nordisk

U.S. Sen. Bernie Sanders (I-Vt.) sent letters to Sanofi SA and Novo Nordisk A/S executives on March 1, urging them to follow Eli Lilly and Co.’s example in cutting prices for their insulin products, offering more affordable access for Americans with diabetes. Industry leaders, however, have long argued that the problem goes far beyond list price, as pharmacy benefit managers and health plans have simply not passed their rebates onto consumers. Read More

FDA rejects EUA for Veru’s sabizabulin, at least for now

Shares of Veru Inc. hit a 52-week low March 3 after the U.S. FDA declined to grant an emergency use authorization (EUA) for sabizabulin for use in hospitalized adults with moderate to severe COVID-19 who are at high risk for acute respiratory distress syndrome. The decision comes as little surprise, given the negative advisory panel vote in November, but the agency’s wording might suggest potential use for the microtubule disruptor in the future. Read More

Appointments and advancements for March 3, 2023

New hires and promotions in the biopharma industry, including: Aadi, Foundery, Hansa, Personalis. Read More

Financings for March 3, 2023

Biopharmas raising money in public or private financings, including: Cidara, Sangamo, Summit. Read More

In the clinic for March 3, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Amniotics, Biovie, BMS, Brim, Inovio, Janssen, Organogenesis, Poolbeg, Sanofi, Sobi. Read More

Other news to note for March 3, 2023

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Augustine, Cormedix, Oculis, Sisaf. Read More

Regulatory actions for March 3, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Aldeyra, Alvotech, Astrazeneca, Checkpoint, Genenta, Intellia, Santhera, Serda, Valneva. Read More

Money raised by biopharma

Total raised in public, private and other financings of biopharma companies, comparing 2023 vs. 2022 vs. 2021 vs. 2020 vs. 2019. Read More

Biopharma money raised: Jan. 1-March 2, 2023

Year-to-date money raised in public, private and other financings of biopharma companies. Read More

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