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Home » Newsletters » BioWorld

BioWorld

Aug. 23, 2023

View Archived Issues
Cancer cells being destroyed by immunotherapy

Lucky leak? TIGIT targeters rise on accidental disclosure by Roche

The narrative of TIGIT-targeting immunotherapy development, beset by negative news in recent months, has found a positive plotline again, thanks to what Roche Holding AG referred to as “an inadvertent disclosure” of a second interim analysis from the phase III Skyscraper-01 study testing anti-TIGIT candidate tiragolumab with anti-PD-L1 antibody Tecentriq (atezolizumab) in non-small-cell lung cancer. Read More

Rapport adds $150M in series B to accelerate push into precision neuromedicine

Rapport Therapeutics Inc. raised $150 million in a series B round, less than six months after unveiling its $100 million series A investment. It’s further evidence that its distinctive precision neuromedicine approach has gained traction with some deep-pocketed investors and adds further momentum both to its clinical development and its discovery research efforts. Read More
Blue-and-red-vials.png

Regeneron gets $326M through 'Project Nextgen' as HHS prepares for the future of COVID

The COVID-19 pandemic might be officially over, but future variants could still pose a threat, and serious health consequences of the causative virus continue to arise, a fact that has prompted the U.S. government to offer Regeneron Pharmaceuticals Inc. about $326 million to develop and manufacture a next-generation COVID-19 monoclonal antibody therapy. Read More

Fore closes its series D to advance BRAF alterations drug

Fore Biotherapeutics Inc. has closed on a $75 million series D financing so that it can continue developing its lead asset, plixorafenib, an oral small molecule that selectively inhibits BRAF alterations. Read More
Blood cells and destruction of cancer cell

Verismo, U Penn team up on two CD19 binders for novel CAR T

Verismo Therapeutics Inc., the U.S. subsidiary of South Korea’s HLB Co. Ltd., inked a license agreement with the University of Pennsylvania for two newly discovered CD19 binders – one of which will be used to develop Synkir-310, its investigative CAR T therapy for blood cancers. Read More
Clovibactin art concept

Cage fight could make for resistance-resistant antibiotic

A newly discovered antibiotic has been shown to block the synthesis of bacterial cell walls via immutable targets, raising the prospect of a class of drugs that will not lose effect through the development of antimicrobial resistance. Clovibactin, isolated from soil bacteria, targets the cell wall precursor molecules lipid II, lipid III and undecaprenyl phosphate (C55PP), all of which have a pyrophosphate group in common. Read More

BioWorld Insider Podcast – The struggle is real: The first half of 2023 was an uphill climb

Guests Karen Carey, BioWorld’s managing editor, and Mike Ward, Clarivate’s global head of Life Sciences and Healthcare Thought Leadership, discuss the deals, financing and M&A landscape for the first half of 2023 and how U.K. biopharmas are faring post Brexit. Read More

Appointments and advancements for Aug. 23, 2023

New hires and promotions in the biopharma industry, including: Abivax, Ajax, Alpine Immune Sciences, Alterome, Biontech, Immvira, Neuron23, Ray. Read More

Financings for Aug. 23, 2023

Biopharmas raising money in public or private financings, including: Janone, Sobi. Read More

In the clinic for Aug. 23, 2023

Clinical updates, including trial initiations, enrollment status and data readouts and publications: Eli Lilly, Geneos, Genethon, Index, KIintor, Matinas, Recce, South Rampart, Stellas, Ventus. Read More

Other news to note for Aug. 23, 2023

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Aardvark, Agenus, Anti-infective Cures, Apellis, Apexigen, Bayer, Celcuity, Evofem, Ferronova, Gri, Mallinckrodt, Medigene, Merck & Co., Pyxis. Read More

Regulatory actions for Aug. 23, 2023

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Akava, Amgen, Fulcrum, Geron, Janssen, Nascent, Pfizer, Vigeneron, Vincerx. Read More

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