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Home » Newsletters » BioWorld

BioWorld

July 9, 2024

View Archived Issues
Dorsal striatum and its neurons in Huntington's disease

Uniqure silence(r) is golden: AMT-30 shines in HD phase I/II

Uniqure NV shares (NASDAQ:QURE) closed July 9 at $6.67, up $2.89, or 76%, after the firm made public updated interim data including up to 24 months of follow-up findings from 29 treated patients enrolled in the ongoing U.S. and European phase I/II trials of AMT-130 for Huntington’s disease (HD). Read More

Soligenix lights the way with positive T-cell lymphoma data

Soligenix Inc. investors were extremely enthusiastic about the positive interim update for the company’s cancer therapy and light device, Hybryte, for treating for treating early stage cutaneous T-cell lymphoma. The Princeton, N.J.-based company’s stock (NASDAQ:SNGX) soared a whopping 464% before closing at a more modest but still massive of 271% increase to $7.42 each on July 9. Read More
White Euro symbol on blue background

Scirhom targeting iRhom2 in autoimmune disease with €63M series A

Autoimmune disease specialist Scirhom GmbH has raised €63 million (US$68 million) in a series A to take an antibody against iRhom2, an enzyme that regulates TNF-alpha secretion, into the clinic. The company has approval for a phase I trial in healthy volunteers that will start later this year, with plans for proof-of-concept trials in rheumatoid arthritis and inflammatory bowel disease to follow. Read More

Few surprises in FTC’s interim report on PBM practices

The redacted interim report released July 9 of an ongoing FTC investigation into pharmacy benefit managers (PBMs) shed little, if any, new insight into PBM practices and how they impact availability and pricing of prescription drugs in the U.S. Read More
Kidneys

Biocity’s SC-0062 hits endpoint in chronic kidney disease trial

Biocity Biopharmaceutics Co. Ltd.’s selective endothelin receptor type A antagonist, SC-0062, met the primary endpoint of reducing proteinuria in a phase II chronic kidney disease trial. The candidate showed a clinically meaningful and statistically significant reduction in proteinuria, with a clear dose-response relationship and good safety profile. Read More

Discgenics’ cell therapy on phase III track for disc degeneration

Phase I/II data of IDCT (rebonuputemcel), a cell therapy in development for chronic and progressive lumbar degenerative disc disease and one that has both regenerative medicine advanced therapy and fast track designations in the U.S., has been published in the International Journal of Spine Surgery for showing statistically significant improvements in pain, disability and quality of life. Read More

Alteogen’s Altos nabs ₩24.5B in series B to develop new eye drug

Altos Biologics Inc., founded as an eye disease-focused subsidiary of Alteogen Inc. in 2020, raised ₩24.5 billion (US$17.7 million) in a series B financing round to advance its pipeline of therapeutics for eye-related conditions, including age-related macular degeneration (AMD). Daejeon, South Korea-based Alteogen said July 9 that the funds raised will be funneled to develop OP-01, Altos’ candidate therapy for AMD. Read More

First Circuit: Frequency class action brushstrokes no ‘van Gogh’

Just because a statement turns out to be false doesn’t mean it was intended to be, the U.S. Court of Appeals for the First Circuit said in tossing a stockholder class action against Frequency Therapeutics Inc., now part of Korro Bio Inc. Read More

Best of BioWorld: Q2

A selection of top news from April to June 2024. Read More

‘We're always on the lookout for what's next’

From no hope to viable treatments, BioWorld  is there to cover the breakthroughs in medicine. Listen to Randy Osborne explain why the BioWorld  team is ‘always on the lookout for what's next.’ Read More

Appointments and advancements for July 9, 2024

New hires and promotions in the biopharma industry, including: Agomab, Aktis, Annovis, Axoltis, Bpgbio, Cel-Sci, Curve, Etherna, Imcheck, Immunic, Longeveron, Newcells, Nocion, Pharmaessentia, Stalicla, Sutro, Vectory, Vyne. Read More

Financings for July 9, 2024

Biopharmas raising money in public or private financings, including: Smartcella, Trevena, Virpax. Read More

In the clinic for July 9, 2024

Clinical updates, including trial initiations, enrollment status and data readouts and publications: AB Science, Cellprothera, Hillevax, Ideaya, Sirnaomics. Read More

Other news to note for July 9, 2024

Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Aerovate, Boehringer, Emergent, Indivior, J&J, Just-Evotec, Kinetic, Pari, Sandoz, Scisparc, Spexis, Tuhura. Read More

Regulatory actions for July 9, 2024

Regulatory snapshots, including global drug submissions and approvals, clinical trial approvals and other regulatory decisions and designations: Adicet, Alteogen, Defence, Mirium, Outlook, Sellas. Read More

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