BioWorld Science

April 9, 1998

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CombiChem and Icos announce drug discovery collaboration

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Mitotix describes novel inhibitors of the CDK/cyclin complexes

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NPY Y1 receptor ligands for eating and cardiovascular disorders

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New COX-2-selective compounds in development at Merck Frosst

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Novel GH secretagogues disclosed by Novo Nordisk

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MS&D describes novel class of antimigraine agents

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EGFR tyrosine kinase inhibitor from Novartis will proceed to clinical testing

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Chemistry of new immunosuppressive triterpenoid elucidated by Merck & Co.

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Flk-1/KDR receptor tyrosine kinase inhibitor SU-5416 characterized at ACS meeting

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New agents for BPH emerge from Synaptic/Merck & Co. collaboration

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VIMRx and Columbia U. form new drug discovery and development company

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Interneuron receives fast track designation for CerAxon

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TNFR:Fc evaluated clinically for congestive heart failure

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Cytovia raises USD 10 million for development and commercialization of proprietary technology

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Pharmacokinetic/safety results reported from ongoing phase I trial of Spartaject busulfan

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Cyclic depsipeptide from Streptomyces induces apoptosis in tumor cells

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Klinge identifies new apoptosis inducers active against MDR cell lines

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Chinese scientists discover novel antitumor antibiotic

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Hokuriku Seiyaku seeks development partners for novel antihistamine

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New cell therapy developed at Wistar Institute shows potential as chemotherapy adjuvant

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PKCbeta inhibitor from Lilly may potentiate effects of radio- and chemotherapy

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Mechanism of cytotoxic effect of ImmTher

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Aplidine evaluated for activity in animal models of lymphoma, prostate and gastric cancer

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