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BioWorld Science

Sep. 27, 2000

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Cyclopamine interferes with genetic cancer signaling pathways

BPT and Pfizer join forces for pulmonary and systemic disease drug development

Oxford GlycoSciences makes considerable progress during first six months of 2000

Telik and Genaissance complete joint estrogen receptor research

HIV viral protein mutations focus potential vaccine development

Allergy researchers clarify IL-9-eosinophil interaction

Vivus seeks FDA approval to begin female sexual dysfunction trial

Immtech enters collaborative project for tuberculosis treatment

Zometa deemed approvable by FDA

Alexion acquires Prolifaron

Axcan licenses sulfated compounds for prevention of colorectal polyps

New COX-2 inhibitors from Uriach have high potency, selectivity and oral antiinflammatory activity

Plant-derived lignan demonstrates inotropic and antidiuretic effects

Merck Frosst describes efforts to obtain PDE4 inhibitors with improved properties

R.W. Johnson investigates impact of modifications to linezolid molecule on antibacterial activity

Novel drug target identified for hepatitis B

New alpha1/alpha2-adrenoceptor partial agonist S-19014 shows potential in migraine Rx

Portuguese investigators identify peripheral COMT inhibitor

FDA approves Trisenox for APL only three years after U.S. studies began

Novel class of bacterial DNA gyrase inhibitors presented at ICAAC by Pfizer

Novel compounds from American Home Products display high affinity for 5-HT1A receptors

AHP presents newest PTPase inhibitors with blood glucose-lowering activity

Benzimidazole FBPase inhibitors and their use in diabetes and related disorders

European patent issued to Pfizer covers new NPY antagonists

Thyroid receptor ligands particularly useful in the treatment of obesity

GABA-A receptor-selective compounds synthesized at Merck

New factor Xa inhibitors with therapeutic and diagnostic uses

Combinations with synergistic antitumor activity claimed by Pharmacia

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