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BioWorld Science

May 24, 2002

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Novel NO donors prepared at Merck

Citrullimycines isolated from Streptomyces sp.

Anti-HIV agents patented by Janssen, CNRS and Institut Curie

Akzo Nobel presents new LH receptor agonists

Antiamyloidogenic phenoxazines described for treatment, diagnosis of Alzheimer's disease

Thrombin inhibitors in development at 3-Dimensional

Antiproliferative sulfones prepared and tested at Temple University

Intranasal NP-7557 shows preclinical potential in Alzheimer's disease

Avera acquires neuromuscular blockers from GSK

RPR-238677 identified as a potent, orally available p38 MAP kinase inhibitor

Clinical trial of mucoregulator MSI-1995 versus antiinflammatory agent ongoing in asthma patients

Broad-spectrum prokinetic agent discovered at Kissei

Antisense oligonucleotide targeting TGF-beta2 shows promise for malignant glioma, other solid tumors

Interim phase I results indicate safety and efficacy of Kosan's epothilone derivative

VML-670 enters phase II program for antidepressant-related sexual dysfunction

Tenofovir topical gel enters phase I trial for prevention of vaginal transmission of HIV

GSK and Nobex form alliance for oral insulin development and commercialization

Phase II data in NSCLC support Pivanex as a novel approach to cancer therapy

Approval recommended for Amevive in psoriasis

Remodulin approved for pulmonary arterial hypertension

AstraZeneca and Shionogi to comarket Crestor in Japan

Clinical efficacy and safety data presented for ET-743 at ASCO meeting

Efficacy of valsartan shown in a murine model of pulmonary fibrosis

ZD-2574 attenuates cardiopulmonary dysfunction in acute pulmonary thromboembolism

SP-600125 effective in models of allergic asthma according to data presented at ATS 2002

New data on sildenafil presented at the ATS conference

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