Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 14, 2002

View Archived Issues

Novel 5-HT1B antagonists with utility in depression identified at GSK

New adenosine A1 agonists discovered by GSK researchers

Merck scientists present novel inhibitors of factor Xa and/or factor VIIa

Sankyo describes the isolation of new antifungal agents from Phoma sp.

Series of integrin antagonists for asthma and other disorders prepared at Merck & Co.

Cholesterol-lowering efficacy of SMP-500, a novel ACAT inhibitor, in hyperlipidemic hamsters

Oregovomab enhances killer T-cell responses in apoptotic ovarian cancer cells

Pretreatment of solid tumors with NHS76/PEP2 improves efficacy of chemotherapy in mice

Emodin accelerates pancreatic regeneration in acute pancreatitis in rats

Orally active 5-HT2C receptor agonist synthesized at Vernalis as potential antiobesity agent

SLV-314: neurochemical and behavioral effects detailed at Neuroscience 2002

Binding profile of atypical antipsychotic agent SM-13496

Exanta proves superior to routinely used enoxaparin for reducing risk of VTE in major surgery

Oprelvekin reported to increase platelet counts in hepatitis C patients

Potential novel use for PPARgamma agonists discussed at AASLD meeting

Improved safety profile reported for ribavirin prodrug viramidine

Potential use of the antisense oligonucleotide ISIS-14803 in chronic HCV

Commit lozenge approved by the FDA for over-the-counter sale

Drug safety announcement regarding Refludan

Seattle Genetics releases clinical and preclinical updates

Recombinant alpha 1-antitrypsin topical gel enters clinical trials

Accelerated approval plan for KRX-101

Johnson & Johnson to acquire OraPharma

Serono and Amgen sign license agreement for multiple sclerosis product

Vertex advances Aurora kinase inhibitor into preclinical development

Immtech International completes efficacy trials of DB-289

Phase II clinical trial initiated to evaluate the efficacy of 17beta-estradiol against restenosis

Popular Stories

Today's news in brief
BioWorld
SCAN is core circuit affected in Parkinson’s disease
BioWorld Science
Parkinson’s disease (PD) is a neurodegenerative disorder that affects movement, and tremor is one of its signatures. But it is a much more wide-ranging disorder,...
TL1A is overexpressed in hidradenitis suppurativa
BioWorld Science
Despite the availability of advanced therapeutic options, about 40%-50% of patients with hidradenitis suppurativa do not achieve significant improvement in...
IL-22 and TL1A, a robust couple for diagnosing hidradenitis suppurativa
BioWorld Science
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease with strong association with psoriasis and inflammatory bowel disease (IBD). While some...
Inhibiting the NLRP3 inflammasome for cognitive impairment, stroke
BioWorld Science
Vascular cognitive impairment and dementia (VCID) and cerebral small vessel disease are among the leading causes of dementia, where inflammation is known to play...