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BioWorld - Sunday, December 7, 2025
Home » Newsletters » BioWorld Science

BioWorld Science

Nov. 14, 2002

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Novel 5-HT1B antagonists with utility in depression identified at GSK

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New adenosine A1 agonists discovered by GSK researchers

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Merck scientists present novel inhibitors of factor Xa and/or factor VIIa

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Sankyo describes the isolation of new antifungal agents from Phoma sp.

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Series of integrin antagonists for asthma and other disorders prepared at Merck & Co.

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Cholesterol-lowering efficacy of SMP-500, a novel ACAT inhibitor, in hyperlipidemic hamsters

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Oregovomab enhances killer T-cell responses in apoptotic ovarian cancer cells

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Pretreatment of solid tumors with NHS76/PEP2 improves efficacy of chemotherapy in mice

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Emodin accelerates pancreatic regeneration in acute pancreatitis in rats

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Orally active 5-HT2C receptor agonist synthesized at Vernalis as potential antiobesity agent

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SLV-314: neurochemical and behavioral effects detailed at Neuroscience 2002

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Binding profile of atypical antipsychotic agent SM-13496

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Exanta proves superior to routinely used enoxaparin for reducing risk of VTE in major surgery

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Oprelvekin reported to increase platelet counts in hepatitis C patients

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Potential novel use for PPARgamma agonists discussed at AASLD meeting

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Improved safety profile reported for ribavirin prodrug viramidine

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Potential use of the antisense oligonucleotide ISIS-14803 in chronic HCV

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Commit lozenge approved by the FDA for over-the-counter sale

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Drug safety announcement regarding Refludan

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Seattle Genetics releases clinical and preclinical updates

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Recombinant alpha 1-antitrypsin topical gel enters clinical trials

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Accelerated approval plan for KRX-101

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Johnson & Johnson to acquire OraPharma

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Serono and Amgen sign license agreement for multiple sclerosis product

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Vertex advances Aurora kinase inhibitor into preclinical development

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Immtech International completes efficacy trials of DB-289

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Phase II clinical trial initiated to evaluate the efficacy of 17beta-estradiol against restenosis

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