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BioWorld - Sunday, May 3, 2026
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Home » Aria ready for CAARs? Bid by Penn-sprung Cabaletta targets B cells to fight PV
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Aria ready for CAARs? Bid by Penn-sprung Cabaletta targets B cells to fight PV

Nov. 9, 2018
By Randy Osborne
Cabaletta Bio Inc. CEO Steven Nichtberger noted that his firm is "not the first to develop chimeric T cells as therapeutics, [but] we are the first to develop them in a way that leverages the potential of T cells to specifically eliminate only the B cells that cause autoimmune disease, thus sparing the healthy cells," and he told BioWorld that the lead indication – mucosal pemphigus vulgaris (PV) – represents a "hallmark for potential efficacy in a whole host of B-cell-mediated autoimmune diseases."
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