I. FINANCING OF PRIVATE BIOTECHNOLOGY COMPANIES: $174.96M

Company

Location

Date

Amt. (M)

Details


Abeome Corp.

Athens, Ga.

4/14

$1.5

Abeome received $1.5M in seed financing from two Athens investors

Acusphere Inc.

Watertown,
Mass.

4/21

$20

Acusphere raised $20M in an eighth round led by Thomas Weisel Capital Partners LLC; other investors were BA Venture Partners; Polaris Venture Partners; BancBoston Ventures; Audax Group; Technology Funding Venture Capital; Burr, Egan, Deleage & Co.; and HBM Bioventures

Ansata
Therapeutics
Inc.

La Jolla, Calif.

4/10

$5

Ansata raised $5M in a Series A, which began last year; investors include Avalon Ventures and Domain Associates

Bioline
Therapeutics

Zichron Ya'akov, Israel

4/9**

US$11

Bioline raised US$11M in seed financing; founders are Teva Pharmaceutical Industries Ltd., Giza Venture Capital, Pitango Venture Capital and Hadasit

Biomer
Technology Ltd.

Runcorn, UK

4/16**

£0.3 (US$0.46)

Biomer raised US$459,000 in an initial funding round

CellFactors plc

Newport, UK

4/9**

£2.13 (US$3.3)

CellFactors raised US$3.3M in the first close of its current funding round

Cetek Corp.

Marlborough,
Mass.

4/2

$6

Cetek raised $6M in a private equity financing; investors were John and Stephen Davis, James Waters and Gainesborough Investments

Cohesive
Technologies
Inc.

Franklin,
Mass.

4/8

$8.5

Cohesive completed an initial closing of an $8.5M Series B financing round led by Psilos Group Partners; other investors were Mitsubishi Corp. and Oxford Bioscience Partners

Cytokinetics Inc.

South San
Francisco

4/28

$40

Cytokinetics raised $40M in its fifth round; investors were General American Investors, HBM BioVentures, PRM Ventures, Mizuho Capital Co. Ltd., Sevin Rosen Funds, Credit Suisse First Boston Private Equity, Alta Partners, Mayfield Fund, Vulcan Ventures Inc., GlaxoSmithKline and others

Epigenomics AG

Berlin

4/3

€21 (US$22.5)

Epigenomics raised €21M in a Series C round; investors were The Wellcome Trust Ltd., 3i Group, Abingworth, Deutsche Venture Capital DVC, MPM Capital and tbg

GenoWay SA

Lyon, France

4/30**

€3.3 (US$3.7)

GenoWay raised US$3.7M in a private financing with Dassault Developpement, Qualis SA and Rh ne Alpes Creation

Kinexis Inc.

San Francisco

4/23

$0.9

Kinexis received $900,000 in a private placement with InvestBioVentures Kinexis GP

MicroIslet Inc.

San Diego

4/2

$12

MicroIslet raised $12M from Fusion Capital Fund II LLC

NimbleGen
Systems Inc.

Madison,
Wis.

4/16

$12.5

NimbleGen raised $12.5M in a Series D round led by Schott Nexterion; other investors were ITX Corp., Skyline Ventures, Tactics II Investments LLC, Baird Venture Partners, Venture Investors Management LLC, the State of Wisconsin Investment Board and the Wisconsin Alumni Research Foundation

Oxxon
Pharmaccines
Ltd.

Oxford, UK

4/14

US$23

Oxxon raised US$23M in a private round led by Questar Capital Management; other investors were Isis Capital, NIF Ventures, Gray Ghost and an unnamed investor

Sloning
BioTechnology

Puchheim,
Germany

4/10

€4.3 (US$4.6)

Sloning closed its Series B round of €4.3M; the round was led by HBM Partners, and included investments by DEWB and 3i

II. MILESTONE PAYMENTS AND EQUITY INVESTMENTS FROM EXISTING CORPORATE PARTNERS: $11.2M

Company (Symbol)#*

Partner (Country)

Amt. (M)

Triggering Event

Details (Date)


Axonyx Inc.
(AXYX)

Serono SA (Switzerland)

$1

Milestone payment

Axonyx received $1M from Serono when Serono initiated a Phase I trial of a beta-sheet breaker peptide for the treatment of Alzheimer's disease (4/24)

Chemokine
Therapeutics
Corp.* (Canada)

PPD Inc.

ND

Equity investment

PPD made an equity investment in Chemokine to continue development of a peptide derived from a particular chemokine that may make the peptide useful as a blood recovery therapeutic agent (4/17)

ChondroGene
Ltd.
(Canada; VSE:YDG)

Pfizer Inc.

C$1.58 (US$1)

Milestone payment

ChondroGene received the payment after achieving a milestone in the target identification program for osteoarthritis (4/8)

Epimmune Inc.
(EPMN)

Genencor International Inc. (GCOR)

ND

Milestone payment

Epimmune received the payment for the identification of epitope candidates for inclusion in the human papillomavirus therapeutic vaccine being developed by the companies (4/2)

Inex
Pharmaceuticals
Corp. (Canada; TSE:IEX)

GlaxoSmithKline
plc (UK)

$1.5

Milestone payment

Inex earned the payment after GSK filed with the FDA an investigational NDA to begin trials evaluating the anticancer drug topotecan (4/16)

Isis
Pharmaceuticals

Inc.
(ISIS)

Eli Lilly and Co.

$1.5

Milestone payment

Isis received the payment for its development of ISIS 23722 as part of an antisense drug discovery collaboration (4/21)

Rigel
Pharmaceuticals

Inc.
(RIGL)

Daichi Pharmaceuticals Co. Ltd. (Japan)

ND

Milestone payment

Rigel received the milestone payment in conjunction with the partnership to develop an oncology drug (4/3)

SemBioSys
Genetics Inc.*
(Canada)

AVAC Ltd.
(Canada)

C$2.5 (US$1.7)

Investment

SemBioSys received the investment to complete development of SemBioSys' Strato-Capture Protein A Purification System (4/30)

Stressgen Development Corp. (subsidiary of Stressgen Biotechnologies Corp.; TSE:SSB)

F. Hoffmann-
La Roche Ltd. (Switzerland)

$4.5

Investment and milestone payment

Stressgen received an equity investment of about $3M and a development milestone payment of about $1.5M as part of an agreement for CoVal fusion product candidate HspE7 (4/30)


Notes:

# Unless otherwise indicated, shares are traded on the Nasdaq exchange.

* Denotes privately held company.

** Denotes the date the item ran in BioWorld International.

ND = Not disclosed; TSE = Toronto Stock Exchange; VSE = Vancouver Stock Exchange