Biotech Co.*
(Country; Symbol)

Pharma Co.
(Country)

Product

Terms/Details (Date)


Aastrom
Biosciences Inc.
(ASTM)

CDK Tibbi
Malzeme Ticaret Ltd. Sti. (Turkey) and Capitalife Ltd. (UK)

Cell Production Products

Agreements expand the sales and marketing of Aastrom's Cell Production Products line in Italy and Turkey; CDK will distribute the line in Turkey, while Capitalife will assist Aastrom's subsidiary, Zellera AG, with marketing in Italy (1/13)

Access Pharmaceuticals Inc. (AMEX:AKC)

Zambon Group
(Italy)

Amlexanox

Zambon gained exclusive marketing rights in France, Germany, Holland, Belgium, Luxembourg, Switzerland, Brazil and Columbia and a semi-exclusive license for Italy for amlexanox to treat canker sores; Zambon will pay an up-front licensing fee, make milestone payments and purchase the finished product from Access; the deal could generate up to $6.7M for Access (1/14)

AEterna
Laboratories
Inc. (AELA) and its subsidiary Zentaris AG* (Germany)

German Remedies Ltd. (unit of the Zydus Cadila Group; India)

Impavido (miltefosine)

Agreement for German Remedies to market Impavido in India and Bangladesh (2/27)

AEterna
Laboratories
Inc. (AELA) and its subsidiary Zentaris AG* (Germany)

Hainan Tianwang International Pharmaceutical Co. (China)

Lobaplatin

Hainan Tianwang will manufacture and market Lobaplatin in China; Zentaris will receive a one-time payment of C$4.5M (US$2.9M); Tianwang will manufacture and deliver Lobaplatin to Zentaris or its partners for marketing in all other countries (1/8)

Altus Biologics
Inc.*

Dr. Falk Pharma GmbH (Germany)

TheraCLEC

Dr. Falk Pharma receives exclusive rights to market the product in Europe, while Altus maintains marketing rights throughout the rest of the world, as well as global manufacturing rights; Dr. Falk Pharma will make up-front and milestone payments to Altus, as well as royalty payments upon commercialization (2/12)

Cangene Corp.
(Canada; TSE:CNJ)

Baxter Healthcare
Corp.

WinRho SDF

European marketing and distribution agreement for WinRho SDF; Baxter will market and distribute the product in Europe, excluding Portugal, for treating immune thrombocytopenic purpura (3/14)

Cellegy Pharmaceuticals
Inc.
(CLGY)

PDI Inc.

Tostrex Gel

Exclusive license agreement to commercialize the product in North America; Cellegy received $15M, and will receive a $10M milestone payment contingent on FDA approval of Tostrex Gel; PDI also will make royalty payments on net sales, ranging from 20% to 30%; Cellegy will supply the product, but will be reimbursed for manufacturing costs (1/2)

Crucell NV
(the Netherlands;
CRXL)

Aventis Pasteur
(France)

Technology related to viral vaccines

Aventis Pasteur will use Crucell's cell-based vaccine manufacturing technology to develop and commercialize next-generation vaccines; Crucell will receive up-front payments, milestone payments and royalties on future product sales (1/27)

DynPort Vaccine
Co.*
(joint venture between DynCorp and Porton International plc; UK)

MicroTest Laboratories Inc.

Recombinant vaccines against botulinum neurotoxins

MicroTest received a $1.22M contract to provide aseptic manufacturing support for the production of a series of recombinant vaccines (2/11)

Eurand
International

SpA*
(Italy)

Kyowa Hakko
Kogyo Co. Ltd. (Japan)

An orally administered fast-melt tablet technology

Eurand acquired worldwide pharmaceutical rights to the technology, as well as the manufacturing processes for the product; it intends to market the product in combi- nation with Microcaps, its taste-masking technology (1/21)

GeneLink Inc.
(OTC BB:GNLK)

FoodScience
Corp.

GeneLink's genetic assessment technology

The agreement authorizes FoodScience to distribute GeneLink's DNA Collection Kit and Nutragenetic Profile Assessments and related products (1/29)

ILEX Oncology
Inc.
(ILXO)

Schering AG
(Germany)

Campath

Agreement giving Schering rights to develop, sell and distribute Campath in Japan, China and the Asian Pacific Basin (2/5)

Ligand Pharmaceuticals
Inc.
(LGND)

Organon Pharmaceuticals USA Inc.

Avinza

Co-promotion agreement for Avinza; it is set for 10 years and involves only the U.S.; Organon has an option to extend the agreement to 2017 by making a $75M payment to Ligand (2/25)

SkyePharma
plc
(UK; SKYE)

Shire Pharmaceuticals plc (UK)

Solaraze

Licensing agreement giving Shire exclusive rights to manufacture, distribute and sell Solaraze, a topical therapy for actinic keratosis, in Australia, New Zealand, South Africa and certain other countries in the Pacific Rim; Shire will receive up to 2.2M (US$3.5M) comprising an up-front payment and milestone payments (1/15)

Trimeris Inc.
(TRMS) and F. Hoffmann-La Roche Ltd. (Switzerland)

Chronimed Inc.

Fuzeon

U.S. distribution agreement for Fuzeon (3/20)


Notes:

# The information in the chart does not cover agricultural agreements or those between biotech companies.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

AMEX = American Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; TSE = Toronto Stock Exchange