Company*
(Country; Symbol)

Company*
(Country; Symbol)

Product

Terms/Details (Date)

Abgenix Inc.
(ABGX)

CuraGen Corp.
(CRGN)

CR002

Abgenix will manufacture CuraGen's CR002 antibody and has the right of first offer to manufacture additional antibodies stemming from the alliance (1/9)

Alexion Pharmaceuticals
Inc. (ALXN)

Lonza Biologics Ltd.* (Switzerland)

Eculizumab

Product supply agreement for Lonza to commercially manufacture Alexion's C5 complement inhibitor antibody, eculizumab (1/6)

Amersham Biosciences
(unit of Amersham
plc; UK; NYSE:AHM; LSE:OSE)

Thermo Electron Corp. (NYSE:TMO)

Ettan Maldi-ToF Pro mass spectrometer and the Finnigan line of ion trap mass spectrometry systems

The companies will jointly market and sell mass spectrometry-based proteomics solutions designed to help protein scientists in their life sciences research (2/5)

Avanir Pharmaceuticals Inc. (AMEX:AVN)

Drug Royalty USA (subsidiary of Drug Royalty Corp.)

Docosanol 10% cream (Abreva)

Agreement in which Avanir sold for $24.1M a portion of its future royalty stream on North American sales of docosanol 10% cream; Avanir retains rights to 50% of royalties earned on sales of Abreva in excess of $62M a year (12/26)

BioPartners
GmbH* (Switzerland)

Rentschler Biotechnologie
GmbH & Co. KG*
(Germany)

Interferon beta product

Exclusive agreement under which Bio-Partners will receive worldwide marketing exclusivity for an interferon beta product to treat multiple sclerosis; BioPartners will conduct Phase III trials of the product (1/13)

MDL Information Systems Inc.*

SciTegic Inc.*

Pipeline Pilot

Collaboration under which MDL will co-market Sci-Tegic's data analysis and mining tool, Pipeline Pilot, in the life science informatics field, offer consulting services related to the product and license Pipeline Pilot for internal use (1/30)

Nektar
Therapeutics
(NKTR)

The Straumann
Group (Switzerland;
SWX:STMN)

PEG-based hydrogel technology

The Straumann Group will manufacture and supply Nektar's PEG-based hydrogel technology for dental regeneration products; the products would be used by dentists to support the tissue regeneration involved in dental surgery (1/24)

Paracelsian Inc. (OTC BB:PRLN)

Dr. Chip Biotech
Inc.* (Taiwan)

Ah-Immunoassay

Dr. Chip Biotech gains exclusive rights to manufacture, develop and sell Paracelsian's Ah-Immunoassay in China and Southeast Asia; Paracelsian will get license fees and royalties (1/31)

Skyepharma plc
(UK; SKYE)

Endo
Pharmaceuticals
Inc. (ENDP)

DepoMorphine and Propofol IDD-D

Endo gains exclusive rights to market and distribute the products; SkyePharma receives a $25M up-front payment, as well as potential milestones and royalties that push the value of the deal to over $100M (1/3)

Variagenics Inc. (VGNX)

Celera Diagnostics
(joint venture between
Applied Biosystems
Group, NYSE:ABI; and Celera Genomics
Group, NYSE:CRA)

Products for the detection of MTHFR polymorphisms

Variagenics granted a worldwide license to Celera to commercialize products for the detection of MTHFR polymorphisms for applications including assessment of thromboembolic disease risk, including stroke and myocardial infarction (1/14)

Variagenics Inc. (VGNX)

GeneOhm Sciences
Inc.*, Sciona Ltd.*
(UK) and Tm Bio-
science Corp.
(Canada; TSE:TMC)

Variagenics' MTHFR (methyl-enetetrahydrofolate reductase) patent rights

Variagenics granted the companies worldwide nonexclusive rights to commercialize several test formats to detect polymorphisms within the MTHFR gene for applications, including the assessment of thromboembolic disease risk; Variagenics retains the rights to the development of pharmacogenomic applications in oncology and other disease areas (1/16)

Viragen
International Inc.
(OTC BB:VGNI;
subsidiary of Viragen Inc.,
AMEX:VRA)

Genesis Technology Group Inc. (OTC BB:GTEC)

Multiferon

Genesis Technology will help Viragen introduce its natural human alpha interferon drug, Multiferon, into the Chinese market (1/22)

Notes:

#The information in the chart does not cover agricultural agreements.

* Private companies are indicated with an asterisk.

Unless otherwise noted, stock symbols listed are on the Nasdaq market.

AMEX = American Stock Exchange; LSE = London Stock Exchange; NYSE = New York Stock Exchange; OTC BB = Over-the-Counter Bulletin Board; SWX = Swiss Stock Exchange; TSE = Toronto Stock Exchange