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BioWorld - Wednesday, January 7, 2026
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Home » FDA slaps partial hold on Kura’s menin inhibitor trial after patient death
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FDA slaps partial hold on Kura’s menin inhibitor trial after patient death

Nov. 24, 2021
By Richard Staines
Another drug from the emerging menin inhibitor drug class has hit safety issues, after the FDA put an early stage acute myeloid leukemia trial of Kura Oncology Inc.’s KO-539 on partial clinical hold because of a patient death. The news from Kura follows safety issues that emerged from Syndax Pharmaceuticals Inc.’s rival SNDX-5613, where an issue with QT prolongation emerged in at least 5% of patients in otherwise encouraging phase I/II trial results announced in April.
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