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BioWorld - Friday, September 29, 2023
Home » Topics » Conferences

Conferences
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Radiopharmaceutical illustration
Diagnostics

Discovery of novel radiotheragnostic agents with improved tumor-to-background ratios

Sep. 21, 2023
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Researchers from University Hospital Basel and Universitätsklinikum Ulm presented the discovery of novel radiotheragnostic candidates targeting C-X-C chemokine receptor 4 (CXCR4), which is highly expressed in various cancers and has been linked to poor prognosis.
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Diagnostics

[68Ga]NOTA-XH05, a LAG-3-targeting PET imaging agent to monitor immunotherapy response

Sep. 21, 2023
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Researchers from Huazhong University of Science and Technology presented the discovery and preclinical evaluation of a novel peptide PET tracer targeting LAG-3, [68Ga]NOTA-XH05, being developed as a candidate for evaluating the efficacy of cancer immunotherapy.
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China in red on globe

Chinabio 2023: As tide turns to China, what will keep biotechs afloat in rocky capital, political seas?

Sep. 20, 2023
By Marian (YoonJee) Chu
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“Why do the top 10 pharmaceutical companies remain in the top 10?” asked Li Chen, founder and CEO of Hua Medicine, to audience members at the Chinabio Partnering Forum in Shanghai on Sept. 20. “[It comes down to] their ability to innovate themselves, but also the capability to acquire technology from partnerships, [to] manufacture and sell in countries like the U.S."
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Diagnostics

[68Ga]PF-381, a radiolabeled peptide for early detection of CD38-positive lymphomas

Sep. 20, 2023
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The discovery of new 68Ga-labeled CD38-targeted peptides for PET imaging was recently discussed by researchers from Peking University First Hospital and China National Center For Nanoscience & Technology.
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Conference data for Sept. 19, 2023: IASLC-WCLC

Sep. 19, 2023
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New and updated clinical data presented by biopharma firms at the International Association for the Study of Lung Cancer, 2023 World Conference on Lung Cancer, including: Astrazeneca, Daiichi.
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Lungs
Respiratory

BTI-615 inhibits TGF-β1 signaling and suppresses lung fibrosis in rats

Sep. 19, 2023
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Transforming growth factor β1 (TGF-β1) is a key mediator of the fibrotic response, and its dysregulation drives the formation of the fibrotic niche, which impairs the capacity of tissue repair, regeneration and homeostasis.
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Pancreas
Diagnostics

Researchers present [124I]IMMU-132, a Trop2-targeting PET probe

Sep. 18, 2023
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Researchers from Peking University Cancer Hospital presented the discovery and preclinical evaluation of [124I]IMMU-132, a trophoblast cell surface antigen 2 (Trop2)-targeting molecular probe for micro-PET imaging.
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Cancer cells
Diagnostics

[177Lu]NGR-RGD-AB, a novel albumin binder radiolabeled heterodimer for theranostic use

Sep. 18, 2023
No Comments
Integrin alphavbeta3 and aminopeptidase N (CD13) are important biomarkers involved in tumor angiogenesis, tumor growth and metastasis. Peptides RGD (Arg-Gly-Asp) and NGR (Asn-Gly-Arg) are the most studied peptides for targeting integrin alphavbeta3 and CD13, respectively.
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3D representation of tumor microenvironment
Cancer

Potent and selective EphA2 peptide binder for the treatment of solid tumors

Sep. 15, 2023
No Comments
Ephrin type-A receptor 2 (EphA2) is a type I transmembrane glycoprotein highly expressed in a wide range of tumors such as bladder, pancreatic, esophageal, colorectal, or non-small-cell lung cancer, among others. Furthermore, in most normal tissues, EphA2 is found at low levels and plays a relevant role in carcinogenesis control and tumor progression modulation.
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Diagnostics

[68Ga]Ga-BCY-18469: a radiotheranostic contrast agent for early detection of breast cancer

Sep. 15, 2023
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Bicycle radionuclide conjugates (BRCs) have been developed as a unique radiotheranostic modality for imaging and targeting of proteins overexpressed by tumors, and they possess favorable drug-like properties allowing for effective delivery of radioisotopes. Researchers from Bicycletx Ltd. recently presented a new BRC that targets ephrin type-A receptor 2 (EphA2), named BCY-18469.
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