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Home » Topics » Conferences

Conferences
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Man piecing together a puzzle
Neurology/psychiatric

Discovery and preclinical results of a Rac1 inhibitor for Alzheimer’s

April 17, 2025
At the 2025 International Conference on Alzheimer’s and Parkinson’s Diseases and Related Neurological Disorders (ADPD), researchers from Beijing Joekai Biotechnology LLC presented the discovery process and preclinical results for 50561.
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Neurology/psychiatric

Alzheimer’s vaccine selectively targets toxic amyloid-β oligomers

April 17, 2025
Promis Neurosciences Inc. recently presented the rational design of an Alzheimer’s disease (AD) vaccine candidate maximizing the selective targeting of toxic amyloid-β oligomers.
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Cross section of brain
Neurology/psychiatric

EPHB3 inhibitor VTT-001 reduces neuroinflammation across multiple animal models

April 17, 2025
Researchers from Violet Therapeutics Inc. presented the discovery of VTT-001, a novel EPHB3 inhibitor designed to target astrocyte-mediated disease mechanisms.
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Drug capsule spilling onto brain
Neurology/psychiatric

Biohaven’s BHV-8000 rescues locomotor deficits in Parkinson’s disease

April 17, 2025
BHV-8000 from Biohaven Pharmaceuticals Inc. is a dual, brain-penetrant, oral small molecule that is highly selective against TYK2 and JAK1 enzymes, which are essential enzymes to the inflammatory response driving the progression of many neuroinflammatory and neurodegenerative diseases, such as Parkinson’s disease (PD).
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Brain and blood cells
Biomarkers

Plasma ANG2 predicts poor outcomes after traumatic brain injury

April 17, 2025
Investigators from the University of Pennsylvania have presented data regarding the relationship of angiopoietin-2 (ANG2) and its prognostic impact on traumatic brain injury (TBI). The ANG2 plasmatic levels were measured in patients with TBI (n=362), orthopedic injury controls (n=89) and healthy controls (n=64).
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Scientist with vial
Infection

Preclinical data on new composite peptide vaccine from Longhorn

April 16, 2025
At the recent European Society of Clinical Microbiology and Infectious Diseases (ESCMID) meeting in Vienna, Longhorn Vaccines & Diagnostics LLC presented data on the neutralizing antibody responses of LHNVD-202, an unconjugated composite peptide vaccine.
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Neurology/psychiatric

Preclinical profile of LY-3954065, a pioneering siRNA for Alzheimer’s disease

April 16, 2025
Researchers from Eli Lilly & Co. reported preclinical data on LY-3954068, a MAPT small-interference RNA (siRNA) strategy in AD models. The therapy is designed to reduce tau protein synthesis by inhibiting the translation of MAPT mRNA, with the goal of effectively lowering all forms of tau.
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Illustration of antibodies attacking nerve cells
Immune

Biohaven’s BHV-1310 shows promise for autoimmune disorders

April 16, 2025
Biohaven Pharmaceuticals Inc. has presented preclinical data on their novel bispecific degrader BHV-1310 for the potential treatment of autoimmune disorders. To date, about 10% of the global population is affected by autoimmune diseases. IgG-lowering agents have suboptimal pharmacology and pharmacodynamic effects and have safety and tolerability challenges.
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Telitacicept packaging

Remegen’s lupus drug surfaces with phase III myasthenia gravis data

April 15, 2025
By Marian (YoonJee) Chu
Remegen Co. Ltd. emerged as a surprise challenger in the generalized myasthenia gravis space, unveiling positive phase III data of its China-approved lupus drug, telitacicept (RCT-18; Tai’ai), in the rare autoimmune neuromuscular disorder at the 2025 American Academy of Neurology conference.
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Viruses

Pandemic potential is plentiful, but the next bug’s specifics are known unknown

April 15, 2025
By Anette Breindl
Compared to other forms of prevention, a unique issue for pandemic preparedness is that it is forever unclear what pathogen, exactly, the world needs to be prepared for. There are an estimated 300,000 viruses that infect mammals; add in birds, and the estimate grows to more than half a million. Some of those viruses are much greater threats than others.
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