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Home » Topics » Conferences

Conferences
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Leukemia illustration
Cancer

Rgenta’s RGT-61159 shows promise for MYB-expressing cancers

June 25, 2025
No Comments
MYB is an oncogenic transcription factor that is often aberrantly expressed in hematologic malignancies, mostly in acute myeloid leukemia (AML). Rgenta Therapeutics Inc. recently presented data for RGT-61159, a potent and selective MYB inhibitor compound that demonstrated cell killing across a panel of MYB-overexpressing leukemic cell lines.
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Illustration of hole in vessel wall with repair process in progress
Hematologic

SV-003 restores coagulation in the preclinical setting

June 25, 2025
No Comments
Bispecific antibodies mimicking coagulation factor VIIIa (FVIIIa) have yielded successful results in the treatment of hemophilia A, but there remain some issues in regard to their production.
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Cancer

New CAIX-targeting 68Ga/177Lu theranostic pair for clear cell renal cell carcinoma

June 25, 2025
No Comments
At the recent meeting of the Society of Nuclear Medicine and Molecular Imaging, Chinese Academy of Medical Sciences and Peking Union Medical College scientists co-presented a carbonic anhydrase IX (CAIX)-targeting 68Ga/177Lu theranostic pair for clear cell renal cell carcinoma (ccRCC) and its preclinical evaluation.
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Art concept for hematologic cancer
Cancer

APG-5918 shows potent activity against T-cell lymphoma

June 23, 2025
No Comments
Therapies against aggressive T-cell lymphomas (TCLs) are limited and treatment resistance to histone deacetylase (HDAC) inhibitors often occurs. Polycomb protein EED is a key member of the polycomb repressive complex 2 (PRC2) complex and is an attractive therapeutic target for TCLs. APG-5918 is an EED inhibitor from Ascentage Pharma Group International Co. Ltd. that has been proven to disrupt the PRC2 functioning and has been tested in preclinical TCL models as a promising approach.
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Doctor pointing at prostate in male anatomy model
Cancer

Study confirms BCL3 as therapeutic target in metastatic prostate cancer

June 23, 2025
No Comments
At the 2025 Annual Congress of the European Association for Cancer Research (EACR), researchers from Cardiff University and collaborators presented their research on the role of BCL3 in tumor progression and the therapeutic potential of TNAT-101.
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Multiple sclerosis
Neurology/psychiatric

At EAN 2025, DEI Hub launches to improve care for all

June 23, 2025
By Anette Breindl
No Comments
In recognition of the fact that diversity, equity and inclusion (DEI) are necessary prerequisites for precision medicine, the European Academy of Neurology (EAN) announced the launch of a DEI Hub at its 11th Congress, which is being held in Helsinki through June 24. “We know now that when we talk about personalized medicine, we have to understand that talking about stroke, for example, in a woman is different than talking about stroke in a man,” EAN president Elena Moro told the audience at the opening session of the conference.
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BIO2025: John Crowley and Martin Makary
BIO 2025

Makary lays out FDA’s path, launches pilot review program

June 20, 2025
By Karen Carey
No Comments
On the same day that FDA Commissioner Martin Makary spoke in a fireside chat during the 2025 Biotechnology Innovation Organization’s International Convention, the agency unveiled a pilot commissioner’s national priority voucher program that will enable companies to receive a shortened FDA review time of one to two months.
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Multiple myeloma art concept
Cancer

COG5 unveiled as a therapeutic target in multiple myeloma

June 20, 2025
No Comments
Multiple myeloma bone disease (MBD) lacks effective biomarkers; recent evidence involves exosomal circRNAs in the progression of cancer, but their roles in the field have not been deeply explored. The aim of this study was to explore the role of component of oligomeric golgi complex 5 (COG5) and shed light on its osteolytic mechanism.
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Breast cancer illustration
Cancer

MLK3 degrader PROTAC reduces oncogenic potential of TNBC cells

June 20, 2025
No Comments
Researchers from the National Cancer Institute and their collaborators have presented data regarding a MLK3-degrading PROTAC, CEP1347-VHL-02, for treating triple-negative breast cancer.
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Dendritic cells
Cancer

EACR 2025: A look into next-generation strategies in cancer

June 20, 2025
By Coia Dulsat
No Comments
At the Annual Congress of the European Association for Cancer Research (EACR) in Lisbon, multiple sessions aimed to provide fresh perspectives on the always challenging treatment of cancer, with a strong focus on innovative strategies.
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