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BioWorld - Thursday, June 8, 2023
Home » Topics » Deals and M&A

Deals and M&A
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3D illustration demonstrating antibody-drug conjugate.

Pyramid in-licenses preclinical TROP2-targeted ADC from Genequantum in deal worth up to $1B

April 14, 2023
By Tamra Sami
No Comments
Pyramid Biosciences Inc. has in-licensed Genequantum Healthcare Co. Ltd.’s preclinical trophoblast cell surface antigen 2 (TROP2)-targeting antibody-drug conjugate (ADC), GQ-1010, in a deal worth up to $1 billion in potential milestones. Under the terms, Pyramid gains exclusive rights to develop and commercialize GQ-1010 globally, excluding greater China (mainland China, Hong Kong, Macau and Taiwan). In exchange, privately held Genequantum, of Suzhou, China, will receive an up-front payment of $20 million and up to an additional $1 billion in milestone payments. Genequantum will also be eligible to receive tiered-based sales royalties.
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Diagram illustration - DBL-4pen-FR

Diabeloop teams up with Novo Nordisk on next-generation insulin pens

April 13, 2023
By Bernard Banga
No Comments
Diabeloop SA reported a partnership with Novo Nordisk A/S. The med-tech is planning to integrate DBL-4pen, its self-learning algorithm for multiple daily injection therapy, into Novo Nordisk's connected, reusable insulin pens: Novopen and Novopen Echo Plus. “Our partnership is designed to deliver more automated solutions to people with diabetes, optimizing outcomes and improving quality of life,” Cecile Ferracci, CCO of from Grenoble, France-based Diabeloop, told BioWorld.
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Specialised Therapeutics obtains rights to market PD-1 inhibitor from CTTQ-Akeso in $73M deal

April 13, 2023
By Doris Yu
No Comments
Specialised Therapeutics Asia Pte Ltd. has inked a $73 million deal with CTTQ-Akeso Biomed Tech. Co. Ltd. to buy the rights to commercialize the latter’s anti-PD-1 antibody in Australia and Southeast Asia.
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Hands holding puzzle pieces with digital globe overlay

Biopharma deals slip in Q1, completed M&As remain low

April 12, 2023
By Karen Carey
No Comments
Despite strong deal activity throughout each of the last two years, the volume and value of partnerships began sliding in the first quarter (Q1) of 2023, while M&As continue to trail several other years.
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Scientists at Aspect Biosystems bioprinter

Aspect and Novo enter a deal worth up to $2.6B

April 12, 2023
By Lee Landenberger
No Comments
In collaborating with Novo Nordisk A/S, privately held Aspect Biosystems Ltd. entered its biggest ever deal that could bring in more than $2.6 billion while advancing its 3D, bioprinted tissue therapeutics technology. The two companies will collaborate to develop up to four diabetes and/or obesity products, a Novo specialty, using implantable bioprinted tissues to replace, repair or supplement human biological functions. The initial target will be type 1 diabetes.
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Cancer cells

Proxygen partners with Merck in $2.6B molecular glue deal

April 5, 2023
By Caroline Richards
No Comments
Merck & Co. Inc. has seen promise in Proxygen GmbH’s molecular glue degrader technology, agreeing to pay the drug discovery company up to $2.55 billion if specified research, development and commercial milestones are met.
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Antibody-drug conjugate illustration

Innate out-licenses antibodies for celiac disease to Takeda in deal worth $400M

April 4, 2023
By Tamra Sami
No Comments
Innate Pharma SA inked a licensing deal that grants Takeda Pharmaceutical Co Ltd exclusive worldwide rights to research and develop antibody-drug conjugates using a panel of selected Innate antibodies against an undisclosed target, with a primary focus in celiac disease.
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Brain illustration

Building ‘Confodence’: Confo enters potential $182M GPCR pact with Daiichi Sankyo

April 4, 2023
By Cormac Sheridan
No Comments
Confo Therapeutics NV closed out March in much the same way as it began the month – with a deal. 
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3D illustration demonstrating antibody-drug conjugate.

Duality out-licenses ADCs in deal that could top $1.7B

April 4, 2023
By Caroline Richards
No Comments
Biontech SE has tapped into two of Duality Biologics Co. Ltd.’s antibody-drug conjugate candidates (ADCs), paying Duality $170 million up front and agreeing on development, regulatory and commercial milestone fees of $1.5 billion or more.
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Brain and DNA

Biorchestra inks potential $861M deal to develop therapies for neurological disorders

April 4, 2023
By Doris Yu
No Comments
Biorchestra Co. Ltd. reached an exclusive research, option and licensing contract with a U.S.-based company to use its targeting technology platform to develop nucleic acid therapies to treat neurological disorders in a deal valued up to $861 million.
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